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Gene Expression Data
Assay Details
Assay
Reference: J:235148 Anderson DM, et al., Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4494-503
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855533
Gene symbol: Tardbp
Gene name: TAR DNA binding protein
Results
Specimen S7A WT: postnatal month 3 (more )
Note: Double labeled: red - Tardbp; green - wheat germ agglutinin.
Structure Level Pattern Image Note
TS28: skeletal muscle Present S7A WT TDP-43 , S7A WT TDP-43 Merge
Specimen S7A KO: postnatal month 3; Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi (more )
Note: Double labeled: red - Tardbp; green - wheat germ agglutinin.
Structure Level Pattern Image Note
TS28: skeletal muscle Strong S7A KO TDP-43 Merge , S7A KO TDP-43 Expression in this mutant is the same as in wild-type.
Specimen S7B WT: postnatal month 3 (more )
Note: Double labeled: red - Tardbp; green - Chat (assay MGI:7855515).
Structure Level Pattern Image Note
TS28: spinal cord Present S7B WT TDP-43 , S7B WT TDP-43/ChAT Merge
Specimen S7B KO: postnatal month 3; Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi (more )
Note: Double labeled: red - Tardbp; green - Chat (assay MGI:7855515).
Structure Level Pattern Image Note
TS28: spinal cord Present S7B KO TDP-43 , S7B KO TDP-43/ChAT Merge Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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