Gene Expression Data
Assay Details
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Assay
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Reference:
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J:261678
Aoidi R, et al., Mek1(Y130C) mice recapitulate aspects of human cardio-facio-cutaneous syndrome. Dis Model Mech. 2018 Mar 13;11(3):dmm031278
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7840125
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Gene symbol:
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Gfap
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Gene name:
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glial fibrillary acidic protein
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Results
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Specimen
6A +/+:
postnatal week 6
(more  )
Specimen
6A +/+:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: neocortex |
astrocyte of the cerebral cortex |
Present |
Regionally restricted |
6A +/+
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Expression in astrocytes in sensory cortex.
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Specimen
6A Y130C/Y130C:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL/J
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Mutant Allele(s):
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Map2k1tm2.1Chrn/Map2k1tm2.1Chrn
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: neocortex |
astrocyte of the cerebral cortex |
Present |
Regionally restricted |
6A Y130C/Y130C
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Increased density of expressing astrocytes in sensory cortex compared to wild type.
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Specimen
6C/D:
postnatal week 6
(more )
Specimen
6C/D:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: neocortex |
astrocyte |
Present |
Regionally restricted |
6D
,
6C
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Expression in astrocytes in sensory cortex.
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| TS28: neocortex |
astrocyte of the cerebral cortex |
Present |
Regionally restricted |
6D
,
6C
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Expression in astrocytes in sensory cortex.
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Specimen
6E/F:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL/J
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Mutant Allele(s):
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Map2k1tm2.1Chrn/Map2k1tm2.1Chrn
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: neocortex |
astrocyte of the cerebral cortex |
Present |
Regionally restricted |
6E
,
6F
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Increased density of expressing astrocytes in sensory cortex compared to wild type.
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Specimen
6G/H:
postnatal week 6
(more )
Note: Double labeled: green - Gfap; red - Rbfox3 (assay MGI:7840128).
Specimen
6G/H:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: green - Gfap; red - Rbfox3 (assay MGI:7840128).
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
hippocampal astrocyte |
Present |
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6H
,
6G
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Expression in astrocytes.
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Specimen
6I/J:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL/J
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Mutant Allele(s):
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Map2k1tm2.1Chrn/Map2k1tm2.1Chrn
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: green - Gfap; red - Rbfox3 (assay MGI:7840128).
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
hippocampal astrocyte |
Present |
Regionally restricted |
6J
,
6I
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Increased number of expressing astrocytes compared to wild type.
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Analysis Tools