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Gene Expression Data
Assay Details
Assay
Reference: J:174095 Cai Z, et al., Loss of shp2-mediated mitogen-activated protein kinase signaling in muller glial cells results in retinal degeneration. Mol Cell Biol. 2011 Jul;31(14):2973-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7788467
Gene symbol: Rho
Gene name: rhodopsin
Results
Specimen 2K WT: postnatal day 120 (more )
Note: Double labeled: red - Rho; green - Rcvrn (assay MGI:7788466).
Structure Cell Type Level Pattern Image Note
TS28: retina outer nuclear layer photoreceptor cell Present 2K WT
Specimen 2K cKO: postnatal day 120; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Double labeled: red - Rho; green - Rcvrn (assay MGI:7788466).
Structure Cell Type Level Pattern Image Note
TS28: retina outer nuclear layer photoreceptor cell Present 2K cKO Severely depleted photoreceptors (complete cell loss in some region) were seen. All layers were further reduced in thickness.
Specimen S3M: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina outer nuclear layer photoreceptor cell Present S3M
Specimen S3N: postnatal day 7; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: retina outer nuclear layer photoreceptor cell Present S3N Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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