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Gene Expression Data
Assay Details
Assay
Reference: J:357470 Hu B, et al., PAK2 is necessary for myelination in the peripheral nervous system. Brain. 2024 May 3;147(5):1809-1821
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7780025
Gene symbol: Pak2
Gene name: p21 (RAC1) activated kinase 2
Results
Specimen 1Ci-iv: postnatal week 3 (more )
Note: Double labeled: red - Pak2; green - Mbp (assay MGI:7780026).
Structure Level Pattern Image Note
TS28: sciatic nerve Present Regionally restricted 1Ciii , 1Ci , 1Cii , 1Civ Expression localized predominantly in myelin.
Specimen 1Cv-viii: postnatal week 3 (more )
Note: Double labeled: red - Pak2; green - Mbp (assay MGI:7780026).
Structure Level Pattern Image Note
TS28: sciatic nerve Present Regionally restricted 1Cvi , 1Cv , 1Cvii , 1Cviii Expression localized predominantly in myelin.
Specimen 1Di-iv: postnatal week 3 (more )
Note: Double labeled: red - Pak2; green - Nefh (assay MGI:7780027).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 1Di , 1Div , 1Diii , 1Dii Expression localized in cytoplasm of neurons.
Specimen S1 1,2: postnatal; Pak2tm1.1Cher/Pak2tm1.1Cher (more )
Note: Double labeled: red - Pak2; green - Mbp (assay MGI:7780026).
Structure Level Pattern Image Note
TS28: sciatic nerve Present S1_2 , S1_1
Specimen S1 3,4: postnatal; Pak2tm1.1Cher/Pak2tm1.1Cher, Tg(Syn1-cre)671Jxm/0 (more )
Note: Conditional mutant. Double labeled: red - Pak2; green - Mbp (assay MGI:7780026).
Structure Level Pattern Image Note
TS28: sciatic nerve Absent S1_3 , S1_4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory