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Gene Expression Data
Assay Details
Assay
Reference: J:78912 Hellstrom M, et al., Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7750905
Gene symbol: Cdh5
Gene name: cadherin 5
Results
Specimen 7a: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain vascular element Present Regionally restricted 7a In brain capillaries, expression largely confined to interendothelial junction.
Specimen 7b: embryonic day 18.5; Pdgfrbtm1Sor/Pdgfrbtm1Sor (more )
Structure Level Pattern Image Note
TS26: brain vascular element Present Regionally restricted 7b Expression more uniformly distributed compared to wild type. Reduced junctional expression and increased cytoplasmic distribution.
Specimen 7c: embryonic day 18.5; Pdgfrbtm1Sor/Pdgfrbtm1Sor (more )
Note: Double labeled: red - Cdh5; green - Fn1 (assay MGI:7750903).
Structure Level Pattern Image Note
TS26: brain vascular element Present Regionally restricted 7c Authors report highly abnormal expression.
Specimen E12.5 wild type not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present
Specimen E12.5 knock out not shown: embryonic day 12.5; Pdgfrbtm1Sor/Pdgfrbtm1Sor (more )
Structure Level Pattern Image Note
TS20: brain Present No difference compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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