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Gene Expression Data
Assay Details
Assay
Reference: J:49434 Farinas I, et al., Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo. Neuron. 1998 Aug;21(2):325-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7735233
Gene symbol: Ntrk3
Gene name: neurotrophic tyrosine kinase, receptor, type 3
Antibody: anti-TrkC
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3F: embryonic day 11.0 (more )
Note: Double labeled: red - Ntrk3; green - BrdU.
Structure Level Pattern Image Note
TS18: dorsal root ganglion Present 3F None of the positive cells had incorporated BrdU.
Specimen 5B: embryonic day 11.0; Ntf3tm1Lfr/Ntf3tm1Lfr (more )
Note: Double labeled: red - Ntrk3; green - TUNEL.
Structure Level Pattern Image Note
TS18: dorsal root ganglion Present 5B Many but not all TUNEL-positive cells were positive. Positive neuronal numbers were drastically reduced.
Specimen 6B/C: embryonic day 11.0 (more )
Note: Double labeled: red - Ntrk3; green - Ntrk2 (assay MGI:7735235).
Structure Level Pattern Image Note
TS18: dorsal root ganglion Present 6B , 6C Neurons coexpressing both Ntrk2/TrkB and Ntrk3/TrkC (especially in medial and posterior parts of the ganglia) as well as neurons expressing only TrkB (especially in anterior parts of the ganglia, where TrkB is very prominent) or TrkC were seen.
Specimen not shown: embryonic day 11.0 (more )
Note: Double labeled: red - Ntrk3; green - Nefm.
Structure Level Pattern Image Note
TS18: dorsal root ganglion Present Coexpressed with Nefm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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