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Gene Expression Data
Assay Details
Assay
Reference: J:314574 Seo H, et al., Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. Mol Brain. 2015 Feb 27;8:13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7716876
Gene symbol: Pvalb
Gene name: parvalbumin
Antibody: anti-parvalbumin (PARV-19)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3B,D: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn1 (assay MGI:7716871).
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 3B , 3D Expressing cells mainly located in stratum pyramidale
TS28: hippocampus stratum oriens Moderate 3B , 3D Relatively moderate expression in stratum oriens.
TS28: CA1 stratum radiatum Trace 3D , 3B Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus molecular layer Trace 3D , 3B Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 3D , 3B Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 3F,H: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn1 (assay MGI:7716871).
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Present 3F , 3H Expressing cells mainly located in stratum pyramidale.
TS28: hippocampus stratum oriens Moderate 3H , 3F Relatively moderate expression in stratum oriens.
TS28: hippocampus molecular layer Trace 3H , 3F Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 3H , 3F Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum radiatum Trace 3H , 3F Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 3J,L: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn1 (assay MGI:7716871).
Structure Level Pattern Image Note
TS28: hippocampus CA3 Strong 3L , 3J Most intense expression in CA3.
TS28: CA3 pyramidal cell layer Present 3J , 3L Expressing cells mainly located in stratum pyramidale.
TS28: hippocampus stratum oriens Moderate 3J , 3L Relatively moderate expression in stratum oriens.
TS28: hippocampus molecular layer Trace 3J , 3L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 3J , 3L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum radiatum Trace 3J , 3L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 3N,P: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn1 (assay MGI:7716871).
Structure Level Pattern Image Note
TS28: dentate gyrus Present 3P , 3N
Specimen 4B,D: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn2 (assay MGI:7716872).
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 4B , 4D Expressing cells mainly located in stratum pyramidale.
TS28: hippocampus stratum oriens Moderate 4D , 4B Relatively moderate expression in stratum oriens.
TS28: CA1 stratum radiatum Trace 4B , 4D Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus molecular layer Trace 4B , 4D Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 4B , 4D Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 4F,H: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn2 (assay MGI:7716872).
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Present 4F , 4H Expressing cells mainly located in stratum pyramidale.
TS28: hippocampus stratum oriens Moderate 4F , 4H Relatively moderate expression in stratum oriens.
TS28: hippocampus molecular layer Trace 4F , 4H Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 4F , 4H Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum radiatum Trace 4F , 4H Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 4J,L: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn2 (assay MGI:7716872).
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Present 4J , 4L Expressing cells mainly located in stratum pyramidale.
TS28: hippocampus stratum oriens Moderate 4L , 4J Relatively moderate expression in stratum oriens.
TS28: hippocampus molecular layer Trace 4J , 4L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 4J , 4L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum radiatum Trace 4J , 4L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 4N,P: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn2 (assay MGI:7716872).
Structure Level Pattern Image Note
TS28: dentate gyrus Present 4N , 4P
Specimen 5B,D: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn4 (assay MGI:7716874).
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 5B , 5D Expressing cells mainly located in stratum pyramidale.
TS28: hippocampus stratum oriens Moderate 5D , 5B Relatively moderate expression in stratum oriens.
TS28: CA1 stratum radiatum Trace 5B , 5D Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus molecular layer Trace 5B , 5D Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 5B , 5D Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 5F,H: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn4 (assay MGI:7716874).
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Present 5F , 5H Expressing cells mainly located in stratum pyramidale.
TS28: hippocampus stratum oriens Moderate 5F , 5H Relatively moderate expression in stratum oriens.
TS28: hippocampus molecular layer Trace 5F , 5H Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 5F , 5H Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum radiatum Trace 5F , 5H Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 5J,L: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn4 (assay MGI:7716874).
Structure Level Pattern Image Note
TS28: hippocampus CA3 Strong 5J , 5L Most intense expression in CA3.
TS28: CA3 pyramidal cell layer Present 5J , 5L Expressing cells mainly located in stratum pyramidale.
TS28: hippocampus stratum oriens Moderate 5J , 5L Relatively moderate expression in stratum oriens.
TS28: hippocampus molecular layer Trace 5J , 5L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum lacunosum Trace 5J , 5L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
TS28: hippocampus stratum radiatum Trace 5J , 5L Very weak expression in stratum radiatum, stratum lacunosum-moleculare compared to stratum pyramidale.
Specimen 5N,P: postnatal day 21 (more )
Note: Double labeled: green - Pvalb; red - Hcn4 (assay MGI:7716874).
Structure Level Pattern Image Note
TS28: dentate gyrus Present 5P , 5N
Specimen 7B,D: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn1 (assay MGI:7716871).
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present Regionally restricted 7B , 7D Expression co-localized with Hcn1 expression in stratum pyramidale.
Specimen 7F,H: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn1 (assay MGI:7716871).
Structure Level Pattern Image Note
TS28: hippocampus CA2 Present 7F , 7H Expression in all subfields of CA.
Specimen 7J,L: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn1 (assay MGI:7716871).
Structure Level Pattern Image Note
TS28: hippocampus CA3 Present 7L , 7J Expression in all subfields of CA.
Specimen 7N,P: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn1 (assay MGI:7716871).
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 7N , 7P
TS28: dentate gyrus hilus Present 7N , 7P
Specimen 8B,D: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn2 (assay MGI:7716872).
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 8B , 8D
TS28: CA1 stratum radiatum Present 8B , 8D
TS28: hippocampus stratum oriens Present 8B , 8D
Specimen 8F,H: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn2 (assay MGI:7716872).
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Present 8F , 8H
TS28: hippocampus stratum oriens Present 8F , 8H
TS28: hippocampus stratum radiatum Present 8F , 8H
Specimen 8J,L: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn2 (assay MGI:7716872).
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Present 8J , 8L
TS28: hippocampus stratum oriens Present 8J , 8L
TS28: hippocampus stratum radiatum Present 8J , 8L
Specimen 8N,P: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn2 (assay MGI:7716872).
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 8N , 8P
TS28: dentate gyrus hilus Present 8N , 8P
Specimen 9B,D: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn4 (assay MGI:7716874).
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 9D , 9B
TS28: CA1 stratum radiatum Present 9D , 9B
TS28: hippocampus stratum oriens Present 9D , 9B
Specimen 9F,H: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn4 (assay MGI:7716874).
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Present 9H , 9F
TS28: hippocampus stratum oriens Present 9H , 9F
TS28: hippocampus stratum radiatum Present 9H , 9F
Specimen 9J,L: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn4 (assay MGI:7716874).
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Present 9J , 9L
TS28: hippocampus stratum oriens Present 9J , 9L
TS28: hippocampus stratum radiatum Present 9J , 9L
Specimen 9N,P: postnatal day 56 (more )
Note: Double labeled: green - Pvalb; red - Hcn4 (assay MGI:7716874).
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 9N , 9P
TS28: dentate gyrus hilus Present 9N , 9P
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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