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Gene Expression Data
Assay Details
Assay
Reference: J:268403 Zhou L, et al., Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development. FASEB J. 2017 Jan;31(1):132-147
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7711839
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki-67 (D3B5; #9129)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 4C E19.5 WT: embryonic day 19.5 (more )
Note: Double labeled: red - Mki67; green - Tnnt2 (assay MGI:7711840).
Structure Cell Type Level Pattern Image Note
TS26: heart cardiac muscle cell Present Regionally restricted 4C WT E19.5 Expression was detected in proliferating cardiomyocytes.
Specimen 4C E19.5 S187A: embryonic day 19.5; Fen1tm5.1Bhsh/Fen1tm5.1Bhsh (more )
Note: Double labeled: red - Mki67; green - Tnnt2 (assay MGI:7711840).
Structure Cell Type Level Pattern Image Note
TS26: heart cardiac muscle cell Present Regionally restricted 4C S187A E19.5 Expression was detected in proliferating cardiomyocytes.
Specimen 4C P1 WT: postnatal day 1 (more )
Note: Double labeled: red - Mki67; green - Tnnt2 (assay MGI:7711840).
Structure Cell Type Level Pattern Image Note
TS27: heart cardiac muscle cell Present Regionally restricted 4C WT P1 More Ki-67-positive proliferating cardiomyocytes were observed in the WT P1 hearts than in the WT E19.5 hearts.
Specimen 4C P1 S187A: postnatal day 1; Fen1tm5.1Bhsh/Fen1tm5.1Bhsh (more )
Note: Double labeled: red - Mki67; green - Tnnt2 (assay MGI:7711840).
Structure Cell Type Level Pattern Image Note
TS27: heart cardiac muscle cell Weak Regionally restricted 4C S187A P1 The number of Ki-67-positive proliferating cardiomyocytes in S187A P1 hearts was significantly lower than that in S187A E19.5 hearts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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