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Gene Expression Data
Assay Details
Assay
Reference: J:51420 Sharma K, et al., LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7709291
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Islet1
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 6a: embryonic day 10.5 (more )
Note: Right ventral quadrant of neural tube. Double labeled: red - Isl1; green - Nkx2-2 (assay MGI:7709296).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 6a Expression in dorsal ventral location.

Specimen 6b: embryonic day 10.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd, Lhx4tm1Ssp/Lhx4tm1Ssp (more )
Note: Right ventral quadrant of neural tube. Double labeled: red - Isl1; green - Nkx2-2 (assay MGI:7709296).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 6b Expression in correct dorsal-ventral location in similar numbers of cells compared to wild type.

Specimen 6c: embryonic day 10.5 (more )
Note: Right ventral quadrant of neural tube. Double labeled: red - Isl1; green - Pax6 (assay MGI:7709297).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 6c Expression in dorsal ventral location.

Specimen 6d: embryonic day 10.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd, Lhx4tm1Ssp/Lhx4tm1Ssp (more )
Note: Right ventral quadrant of neural tube. Double labeled: red - Isl1; green - Pax6 (assay MGI:7709297).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 6d Expression in correct dorsal-ventral location in similar numbers of cells compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory