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Gene Expression Data
Assay Details
Assay
Reference: J:269981 Marcucci F, et al., Distinct timing of neurogenesis of ipsilateral and contralateral retinal ganglion cells. J Comp Neurol. 2019 Jan 1;527(1):212-224
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7708046
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: clone 39.4D5
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4a: embryonic day 14.5 (more )
Note: Triple labeled: blue - Isl1; red - Mki67 (assay MGI:7708047); green - EdU. EdU injected at E13.
Structure Cell Type Level Pattern Image Note
TS22: retina ganglion cell layer retinal ganglion cell Present Regionally restricted 4a In the ventral retina, expression was detected in postmitotic retinal ganglion cells in the peripheral neural retina and the central retina, but not the ciliary margin zone.
Specimen 4b: embryonic day 14.5 (more )
Note: Triple labeled: blue - Isl1; red - Mki67 (assay MGI:7708047); green - EdU. EdU injected at E13.
Structure Cell Type Level Pattern Image Note
TS22: retina ganglion cell layer retinal ganglion cell Present Regionally restricted 4b In the dorsal retina, expression was detected in postmitotic retinal ganglion cells in the peripheral neural retina and the central retina, but not the ciliary margin zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory