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Gene Expression Data
Assay Details
Assay
Reference: J:87768 Niederkofler V, et al., Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28;24(4):808-18
Assay type: RNA in situ
MGI Accession ID: MGI:7707878
Gene symbol: Rgmb
Gene name: repulsive guidance molecule family member B
Probe: mRGMb probe
Probe preparation: labelled with digoxigenin
Results
Specimen 3B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: neural fold Present Regionally restricted 3B Expressed specifically at tips of neural folds.
Specimen 3F/G: embryonic day 12.5 (more )
Note: Double labeled: blue - Rgmb; overlay in green - Rgma (assay MGI:7707876).
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 3F , 3G Expression found laterally apposed to that of Rgma in early postmitotic neurons.
TS20: dorsal root ganglion Strong 3G , 3F High level of expression in dorsal root ganglia.
Specimen 3I/K: embryonic day 14.5 (more )
Note: Triple labeled: blue - Rgmb; red - Hjv (assay MGI:7707882); overlay in green - Rgma (assay MGI:7707876).
Structure Level Pattern Image Note
TS22: thalamus Present Regionally restricted 3I , 3K Expression found laterally apposed to that of Rgma in early postmitotic neurons.
Specimen not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain nucleus Present Regionally restricted Expression in distinct nuclei in the brain.
Specimen 3M: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: hindlimb Absent 3M
Specimen 4C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: superior colliculus Absent 4C
Specimen 4I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: superior colliculus Trace 4I Only faint expression detected.
Specimen 4K: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: retina retinal ganglion cell Present 4K
Specimen 8G: embryonic day 16.5; Rgmatm1Arbr/Rgmatm1Arbr (more )
Structure Level Pattern Image Note
TS24: superior colliculus Present 8G Expression not altered compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory