About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:299191 Kitazawa M, et al., Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645156
Gene symbol: Des
Gene name: desmin
Antibody: DE-R-11 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon maternal transmission. Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: forelimb muscle Present Regionally restricted 3A Mat-Rtl1 delta Merge , 3A Mat-Rtl1 delta Desmin Expression was detected in the adjoining area of the z-disc close to Rtl1.
Specimen 3A WT(m): postnatal newborn (more )
Note: Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: forelimb muscle Present Regionally restricted 3A WT (m) Desmin , 3A WT (m) Merge Expression was detected in the adjoining area of the z-disc close to Rtl1.
Specimen 3B Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon maternal transmission. Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: forelimb muscle Present Regionally restricted 3B Mat-Rtl1 delta Merge , 3B Mat-Rtl1 delta Desmin Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc in an alternated manner with Rtl1, but not merged.
Specimen 3B WT(m): postnatal newborn (more )
Note: Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: forelimb muscle Present Regionally restricted 3B WT (m) Merge , 3B WT (m) Desmin Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc in an alternated manner with Rtl1, but not merged.
Specimen S8C Pat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon paternal transmission. Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted S8C Pat-Rtl1 delta Merge , S8C Pat-Rtl1 delta Desmin Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc.
Specimen S8C WT: postnatal newborn (more )
Note: Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted S8C WT Desmin , S8C WT Merge Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc in an alternated manner with Rtl1, but not merged.
Specimen S8C Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon maternal transmission. Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted S8C Mat-Rtl1 delta Merge , S8C Mat-Rtl1 delta Desmin Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc in an alternated manner with Rtl1, but not merged.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory