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Gene Expression Data
Assay Details
Assay
Reference: J:299191 Kitazawa M, et al., Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645156
Gene symbol: Des
Gene name: desmin
Antibody: DE-R-11 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon maternal transmission. Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: forelimb muscle Present Regionally restricted 3A Mat-Rtl1 delta Merge , 3A Mat-Rtl1 delta Desmin Expression was detected in the adjoining area of the z-disc close to Rtl1.
Specimen 3A WT(m): postnatal newborn (more )
Note: Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: forelimb muscle Present Regionally restricted 3A WT (m) Desmin , 3A WT (m) Merge Expression was detected in the adjoining area of the z-disc close to Rtl1.
Specimen 3B Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon maternal transmission. Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: forelimb muscle Present Regionally restricted 3B Mat-Rtl1 delta Merge , 3B Mat-Rtl1 delta Desmin Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc in an alternated manner with Rtl1, but not merged.
Specimen 3B WT(m): postnatal newborn (more )
Note: Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: forelimb muscle Present Regionally restricted 3B WT (m) Merge , 3B WT (m) Desmin Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc in an alternated manner with Rtl1, but not merged.
Specimen S8C Pat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon paternal transmission. Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted S8C Pat-Rtl1 delta Merge , S8C Pat-Rtl1 delta Desmin Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc.
Specimen S8C WT: postnatal newborn (more )
Note: Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted S8C WT Desmin , S8C WT Merge Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc in an alternated manner with Rtl1, but not merged.
Specimen S8C Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon maternal transmission. Double labeled: green - Des; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: intercostal muscle Present Regionally restricted S8C Mat-Rtl1 delta Merge , S8C Mat-Rtl1 delta Desmin Expression was detected in the adjoining area of the Z-disc; localized on the surface of myofibrils at the Z-disc in an alternated manner with Rtl1, but not merged.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory