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Gene Expression Data
Assay Details
Assay
Reference: J:173231 Gennet N, et al., Doublesex and mab-3-related transcription factor 5 promotes midbrain dopaminergic identity in pluripotent stem cells by enforcing a ventral-medial progenitor fate. Proc Natl Acad Sci U S A. 2011 May 31;108(22):9131-6
Assay type: RNA in situ
MGI Accession ID: MGI:7628011
Gene symbol: Dmrta2
Gene name: doublesex and mab-3 related transcription factor like family A2
Probe: mDmrt5 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A Dmrt5: embryonic day 10.5 (more )
Note: Triple labeled: blue - Dmrta2; red - Lmx1a (assay MGI:7628014); green - Nkx2-2 (assay MGI:7628013).
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 1A Dmrt5 , 1A merge Expression is in the entire medial ventral midbrain.
Specimen 1B Dmrt5: embryonic day 12.5 (more )
Note: Triple labeled: blue - Dmrta2; red - Lmx1a (assay MGI:7628014); green - Nkx2-2 (assay MGI:7628013).
Structure Level Pattern Image Note
TS20: midbrain floor plate Present 1B Dmrt5
TS20: midbrain ventricular layer Present Regionally restricted 1B merge , 1B Dmrt5 Expression is adjacent to the floor plate.
Specimen 1C E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 1C E9.5 Expression is at the midbrain/forebrain border.
TS15: future midbrain Present Regionally restricted 1C E9.5 Expression is at the midbrain/forebrain border.
Specimen 1C E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 1C E10.5 Expression is in the entire medial ventral midbrain.
TS17: telencephalon Present Regionally restricted 1C E10.5 Expression is in the dorsal telencephalon and the main olfactory bulb.
TS17: optic stalk Present 1C E10.5
Specimen 1C E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present 1C E11.5
Specimen 1D Dmrt5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain floor plate Present 1D Dmrt5
TS20: midbrain ventricular layer Present Regionally restricted 1D Dmrt5 Expression is adjacent to the floor plate.
Specimen 1D TH: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain floor plate Present 1D TH
TS20: midbrain ventricular layer Present Regionally restricted 1D TH Expression is adjacent to the floor plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory