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Gene Expression Data
Assay Details
Assay
Reference: J:235672 Nam H, et al., Identification of STAM1 as a novel effector of ventral projection of spinal motor neurons. Development. 2016 Jul 1;143(13):2334-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7623981
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Results
Specimen 2B: embryonic day 10.5 (more )
Note: Double labeled: red - Isl1; green - Stam (assay MGI:7623980).
Structure Cell Type Level Pattern Image Note
TS17: future spinal cord motor neuron Present 2B STAM1/Isl1 , 2B Isl1

Specimen 2C: embryonic day 10.5 (more )
Note: Double labeled: red - Isl1; green - Stam (assay MGI:7623980).
Structure Cell Type Level Pattern Image Note
TS17: future spinal cord motor neuron Present 2C STAM1 , 2C STAM1/Isl1

Specimen 3C WT: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: spinal cord motor neuron Present 3C WT Isl1

Specimen 3C dKO: embryonic day 12.5; Mnx1tm1Jhk/Mnx1tm1Jhk, Isl2tm2Slp/Isl2tm2Slp (more )
Structure Cell Type Level Pattern Image Note
TS20: spinal cord motor neuron Weak Regionally restricted 3C dKO Isl1 Expression in postmitotic motor neurons drastically reduced compared to control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory