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Gene Expression Data
Assay Details
Assay
Reference: J:231585 Arnes L, et al., betalinc1 encodes a long noncoding RNA that regulates islet beta-cell formation and function. Genes Dev. 2016 Mar 1;30(5):502-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7621817
Gene symbol: Ins1
Gene name: insulin I
Results
Specimen 2C +/+ (upper): embryonic day 15.5 (more )
Note: Double labeled: green - Ins1; red - Cpa1 (assay MGI:7621818).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Present 2C +/+ (upper)

Specimen 2C +/- (upper): embryonic day 15.5; Betalinc1tm1Suss/Betalinc1+ (more )
Note: Double labeled: green - Ins1; red - Cpa1 (assay MGI:7621818).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Present 2C +/- (upper)

Specimen 2C -/- (upper): embryonic day 15.5; Betalinc1tm1Suss/Betalinc1tm1Suss (more )
Note: Double labeled: green - Ins1; red - Cpa1 (assay MGI:7621818).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Weak 2C -/- (upper) Number of expressing cells significantly reduced compared to control.

Specimen 2C +/+ (lower): embryonic day 15.5 (more )
Note: Double labeled: green - Ins1; red - Sst (assay MGI:7621819).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Present 2C +/+ (lower)

Specimen 2C +/- (lower): embryonic day 15.5; Betalinc1tm1Suss/Betalinc1+ (more )
Note: Double labeled: green - Ins1; red - Sst (assay MGI:7621819).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Present 2C +/- (lower)

Specimen 2C -/- (lower): embryonic day 15.5; Betalinc1tm1Suss/Betalinc1tm1Suss (more )
Note: Double labeled: green - Ins1; red - Sst (assay MGI:7621819).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Weak 2C -/- (lower) Number of expressing cells significantly reduced compared to control.

Specimen S7a +/+: postnatal day 2 (more )
Note: Double labeled: green - Ins1.
Structure Cell Type Level Pattern Image Note
TS27: islets of Langerhans type B pancreatic cell Present S7a +/+

Specimen S7a +/-: postnatal day 2; Betalinc1tm1Suss/Betalinc1+ (more )
Note: Double labeled: green - Ins1.
Structure Cell Type Level Pattern Image Note
TS27: islets of Langerhans type B pancreatic cell Present S7a +/-

Specimen S7a -/-: postnatal day 2; Betalinc1tm1Suss/Betalinc1tm1Suss (more )
Note: Double labeled: green - Ins1.
Structure Cell Type Level Pattern Image Note
TS27: islets of Langerhans type B pancreatic cell Weak S7a -/- 50% reduction in number of expressing cells compared to control.

Specimen S7c +/+: embryonic day 15.5 (more )
Note: Double labeled: green - Ins1; red - Cpa1 (assay MGI:7621818).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Present S7c +/+

Specimen S7c +/-: embryonic day 15.5; Betalinc1tm1Suss/Betalinc1+ (more )
Note: Double labeled: green - Ins1; red - Cpa1 (assay MGI:7621818).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Present S7c +/-

Specimen S7c -/-: embryonic day 15.5; Betalinc1tm1Suss/Betalinc1tm1Suss (more )
Note: Double labeled: green - Ins1; red - Cpa1 (assay MGI:7621818).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Weak S7c -/- Number of expressing cells significantly reduced compared to control.

Specimen S8 SST/INS: embryonic day 15.5 (more )
Note: Double labeled: red - Ins1; green - Sst (assay MGI:7621819).
Structure Cell Type Level Pattern Image Note
TS23: islets of Langerhans type B pancreatic cell Present Regionally restricted S8_INS , S8_MERGE (1st row) , S8_inset (1st row) No co-expression with Sst.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory