Gene Expression Data
Assay Details
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Assay
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Reference:
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J:314103
Ulmke PA, et al., Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Stem Cell Reports. 2021 Apr 13;16(4):968-984
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7621562
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Gene symbol:
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Esco2
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Gene name:
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establishment of sister chromatid cohesion N-acetyltransferase 2
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Antibody:
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Anti-Esco2
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Detection system:
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Secondary antibody coupled to Alexa Fluor
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Assay notes:
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Two antibodies were listed: MGI:7621472 and MGI:7621474; the antibody used in this assay was not specified.
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Results
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Specimen
1H:
embryonic day 15.5
(more  )
Note: Triple labeled: green - Esco2; red - Eomes (assay MGI:7621559); blue - Pax6 (assay MGI:7621561).
Specimen
1H:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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Triple labeled: green - Esco2; red - Eomes (assay MGI:7621559); blue - Pax6 (assay MGI:7621561).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cerebral cortex |
Present |
Regionally restricted |
1H boxed bottom right
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1H left
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1H boxed top left
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Expression was mainly detected in the germinative zone of the developing cortex, especially the basal aspect. Most of the Esco2+ cells also expressed the intermediate progenitor cell marker Eomes, and to a lesser extent, cells in the transition stage between radial glial progenitor cells (Eomes+Pax6+), and in radial glial progenitor cells (Pax6+).
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