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Gene Expression Data
Assay Details
Assay
Reference: J:217209 Cottle DL, et al., Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. Hum Mol Genet. 2015 Jan 15;24(2):436-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7621423
Gene symbol: Krt6
Gene name: keratin 6
Antibody: keratin 6A antibody (PRB-169P)
Detection system: Alexa Fluor
Results
Specimen 1B Wild type: embryonic day 18.5 (more )
Note: Double labeled: red - Krt6; green - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS26: epidermis Present 1B Wild type
Specimen 1B lx12/lx12: embryonic day 18.5; Abca12tm1Lex/Abca12tm1Lex (more )
Note: Double labeled: red - Krt6; green - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS26: epidermis Present Regionally restricted 1B lx12/lx12 Authors report epidermal thickening and hyperkeratosis associated with hyperproliferative keratins.
Specimen 6G Wild type: embryonic day 18.5 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS26: epidermis Present 6G Wild type
Specimen 6G lx12/lx12: embryonic day 18.5; Abca12tm1Lex/Abca12tm1Lex (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS26: epidermis Present 6G lx12/lx12
Specimen S2E Wild type E17.5: embryonic day 17.5 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS25: epidermis Present S2E Wild type E17.5
Specimen S2E eI12/eI12 E17.5: embryonic day 17.5; Abca12el12/Abca12el12 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:7621422).
Structure Level Pattern Image Note
TS25: epidermis Present S2E eI12/eI12 E17.5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory