About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:262420 Szenker-Ravi E, et al., RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Nature. 2018 May;557(7706):564-569
Assay type: RNA in situ
MGI Accession ID: MGI:7596252
Gene symbol: Lgr4
Gene name: leucine-rich repeat-containing G protein-coupled receptor 4
Probe: Mm-Lgr4 (318321)
Probe preparation: Antisense DNA
Visualized with: Chromogenic
Results
Specimen 2h Lgr4/Rspo2 (upper): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr4; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: forelimb epidermis Absent 2h Lgr4/Rspo2 (upper) No expression in overlying ectoderm.
TS22: forelimb mesenchyme Present 2h Lgr4/Rspo2 (upper)
Specimen 2h Lgr4/Rspo2 (lower): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr4; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: forelimb epidermis Absent 2h Lgr4/Rspo2 (lower) No expression in overlying ectoderm.
TS22: forelimb mesenchyme Present 2h Lgr4/Rspo2 (lower)
Specimen ED5f Lgr4/Rspo2 (upper): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr4; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: lung mesenchyme Weak ED5f Lgr4/Rspo2 (upper) Low levels expression in mesenchyme.
Specimen ED5f Lgr4/Rspo2 (lower): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr4; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: lung mesenchyme Weak ED5f Lgr4/Rspo2 (lower) Low levels expression in mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory