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Gene Expression Data
Assay Details
Assay
Reference: J:262420 Szenker-Ravi E, et al., RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Nature. 2018 May;557(7706):564-569
Assay type: RNA in situ
MGI Accession ID: MGI:7596252
Gene symbol: Lgr4
Gene name: leucine-rich repeat-containing G protein-coupled receptor 4
Probe: Mm-Lgr4 (318321)
Probe preparation: Antisense DNA
Visualized with: Chromogenic
Results
Specimen 2h Lgr4/Rspo2 (upper): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr4; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: forelimb epidermis Absent 2h Lgr4/Rspo2 (upper) No expression in overlying ectoderm.
TS22: forelimb mesenchyme Present 2h Lgr4/Rspo2 (upper)
Specimen 2h Lgr4/Rspo2 (lower): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr4; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: forelimb epidermis Absent 2h Lgr4/Rspo2 (lower) No expression in overlying ectoderm.
TS22: forelimb mesenchyme Present 2h Lgr4/Rspo2 (lower)
Specimen ED5f Lgr4/Rspo2 (upper): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr4; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: lung mesenchyme Weak ED5f Lgr4/Rspo2 (upper) Low levels expression in mesenchyme.
Specimen ED5f Lgr4/Rspo2 (lower): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr4; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: lung mesenchyme Weak ED5f Lgr4/Rspo2 (lower) Low levels expression in mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory