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Gene Expression Data
Assay Details
Assay
Reference: J:237223 Torii H, et al., Septin7 regulates inner ear formation at an early developmental stage. Dev Biol. 2016 Nov 15;419(2):217-228
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7582028
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-Caspase-3-cleaved (Asp175)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 3A/C: embryonic day 10.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Sox2 (assay MGI:7582027).
Structure Level Pattern Image Note
TS17: otocyst epithelium Trace 3C , 3A
Specimen 3B/D: embryonic day 10.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Sox2 (assay MGI:7582027).
Structure Level Pattern Image Note
TS17: otocyst epithelium Present 3B , 3D Increased number of positive epithelial cells and Sox2+ presumptive sensory epithelial cells (quantified in Fig 3C and 3H).
Specimen not shown: embryonic day 11.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Sox2 (assay MGI:7582027).
Structure Level Pattern Image Note
TS19: otocyst epithelium Trace
Specimen not shown: embryonic day 11.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Sox2 (assay MGI:7582027).
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Increased number of positive epithelial cells and Sox2+ presumptive sensory epithelial cells (quantified in Fig 3C and 3H).
Specimen not shown: embryonic day 12.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Sox2 (assay MGI:7582027).
Structure Level Pattern Image Note
TS20: inner ear epithelium Trace
Specimen not shown: embryonic day 12.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Sox2 (assay MGI:7582027).
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Increased number of positive epithelial cells (quantified in Fig 3C). In Sox2+ presumptive sensory epithelial cells, apoptosis seemed to be increased although the increase was not statistically significant (quantified in Fig 3H).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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