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Gene Expression Data
Assay Details
Assay
Reference: J:277791 Sar Shalom H, et al., Balance between BDNF and Semaphorins gates the innervation of the mammary gland. Elife. 2019 Jan 10;8:e41162
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7579233
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: Anti-Beta III Tubulin (TUJ-1 clone, MAB1195)
Detection system: Secondary antibody
Results
Specimen 4-S1 WT: embryonic day 13.5 (more )
Note: Late of the day (16-17). Double labeled: green - Tubb3; red - Ntrk2 (assay MGI:7579214).
Structure Level Pattern Image Note
TS21: mammary mesenchyme Present Regionally restricted 4-S1_WT merge , 4-S1_WT Tuj1 Sensory neuron innervations (coexpressed with Ntrk2) were seen.
TS21: spinal nerve Present Regionally restricted 4-S1_WT merge , 4-S1_WT Tuj1 Sensory neuron innervations (coexpressed with Ntrk2) were seen.

Specimen 4-S1 KO: embryonic day 13.5; Plxna4tm1Matl/Plxna4tm1Matl (more )
Note: Late of the day (16-17). Double labeled: green - Tubb3; red - Ntrk2 (assay MGI:7579214).
Structure Level Pattern Image Note
TS21: mammary mesenchyme Present Regionally restricted 4-S1_KO merge , 4-S1_KO Tuj1 Increased sensory neuron innervations (coexpressed with Ntrk2), compared with the wild-type female.
TS21: spinal nerve Present Regionally restricted 4-S1_KO merge , 4-S1_KO Tuj1 Increased sensory neuron innervations (coexpressed with Ntrk2), compared with the wild-type female.

Specimen 5-S1 WT: embryonic day 13.5 (more )
Note: Late of the day (16-17). Double labeled: green - Tubb3; red - Ntrk2 (assay MGI:7579214).
Structure Level Pattern Image Note
TS21: mammary mesenchyme Present Regionally restricted 5-S1_WT Tuj1 , 5-S1_WT merge Sensory neuron innervations (coexpressed with Ntrk2) were seen.
TS21: spinal nerve Present Regionally restricted 5-S1_WT Tuj1 , 5-S1_WT merge Sensory neuron innervations (coexpressed with Ntrk2) were seen.

Specimen 5-S1 KO: embryonic day 13.5; Plxna4tm1Matl/Plxna4tm1Matl (more )
Note: Late of the day (16-17). Double labeled: green - Tubb3; red - Ntrk2 (assay MGI:7579214).
Structure Level Pattern Image Note
TS21: mammary mesenchyme Present Regionally restricted 5-S1_KO merge , 5-S1_KO Tuj1 Increased sensory neuron innervations (coexpressed with Ntrk2), compared with the wild-type male.
TS21: spinal nerve Present Regionally restricted 5-S1_KO merge , 5-S1_KO Tuj1 Increased sensory neuron innervations (coexpressed with Ntrk2), compared with the wild-type male.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory