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Gene Expression Data
Assay Details
Assay
Reference: J:316994 Lefebvre J, et al., Alternatively spliced isoforms of WT1 control podocyte-specific gene expression. Kidney Int. 2015 Aug;88(2):321-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7576949
Gene symbol: Synpo
Gene name: synaptopodin
Results
Specimen S1B Synpo/WT1 Control: embryonic day 17.5 (more )
Note: Double labeled: green - Synpo; red - Wt1 (assay MGI:7576943).
Structure Level Pattern Image Note
TS25: metanephros Present S1B Control Synpo/WT1 inset , S1B Control Synpo/WT1
Specimen S1B Synpo/WT1 (-KTS-/-): embryonic day 17.5; Wt1tm1Asc/Wt1tm1Asc (more )
Note: Double labeled: green - Synpo; red - Wt1 (assay MGI:7576943).
Structure Level Pattern Image Note
TS25: metanephros Weak S1B (-KTS-/-) Synpo/WT1 inset , S1B (-KTS-/-) Synpo/WT1 Low levels of expression.
Specimen S1B Synpo/WT1 (+KTS-/-): embryonic day 17.5; Wt1tm2Asc/Wt1tm2Asc (more )
Note: Double labeled: green - Synpo; red - Wt1 (assay MGI:7576943).
Structure Level Pattern Image Note
TS25: metanephros Present Regionally restricted S1B (+KTS-/-) Synpo/WT1 inset , S1B (+KTS-/-) Synpo/WT1 Abnormal localization pattern.
Specimen S7C control: postnatal adult (more )
Structure Level Pattern Image Note
TS28: metanephros Present S7C SYNPO control
Specimen S7C Magi2 ko: postnatal adult; Magi2tm1Yhat/Magi2tm1Yhat (more )
Structure Level Pattern Image Note
TS28: metanephros Present S7C SYNPO Magi2 ko Expression levels normal compared to wild type.Expression levels normal compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory