Gene Expression Data
Assay Details
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Assay
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Reference:
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J:316482
Kouwenhoven WM, et al., Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate. Int J Mol Sci. 2021 Nov 23;22(23)
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7576032
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Gene symbol:
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Th
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Gene name:
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tyrosine hydroxylase
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Probe:
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Th probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5C +/+ lateral to medial 1:
embryonic day 14.5
(more  )
Specimen
5C +/+ lateral to medial 1:
(close  )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C +/+ 1
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Expressed in mesodiencephalic dopaminergic neurons.
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Specimen
5C +/+ lateral to medial 2:
embryonic day 14.5
(more )
Specimen
5C +/+ lateral to medial 2:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C +/+ 2
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Expressed in mesodiencephalic dopaminergic neurons.
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Specimen
5C +/+ lateral to medial 3:
embryonic day 14.5
(more )
Specimen
5C +/+ lateral to medial 3:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C +/+ 3
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Expressed in mesodiencephalic dopaminergic neurons.
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Specimen
5C +/+ lateral to medial 4:
embryonic day 14.5
(more )
Specimen
5C +/+ lateral to medial 4:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C +/+ 4
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Expressed in mesodiencephalic dopaminergic neurons.
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Specimen
5C +/+ lateral to medial 5:
embryonic day 14.5
(more )
Specimen
5C +/+ lateral to medial 5:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C +/+ 5
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Expressed in mesodiencephalic dopaminergic neurons.
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Specimen
5C LacZ/LacZ lateral to medial 1:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C LacZ/LacZ 1
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Similar as in the wild-type.
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Specimen
5C LacZ/LacZ lateral to medial 2:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C LacZ/LacZ 2
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Similar as in the wild-type.
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Specimen
5C LacZ/LacZ lateral to medial 3:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5C LacZ/LacZ lateral to medial 4:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C LacZ/LacZ 4
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Similar as in the wild-type.
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Specimen
5C LacZ/LacZ lateral to medial 5:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
midbrain dopaminergic neuron |
Present |
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5C LacZ/LacZ 5
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Similar as in the wild-type.
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Specimen
7E' +/+:
embryonic day 14.5
(more )
Note: Pseudo-overlay: green - Th; red - Tph2 (assay MGI:7576059).
Specimen
7E' +/+:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Pseudo-overlay: green - Th; red - Tph2 (assay MGI:7576059).
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Specimen
7E' LacZ/LacZ:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Pseudo-overlay: green - Th; red - Tph2 (assay MGI:7576059).
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Specimen
S1B WT rostral to caudal 1:
postnatal adult
(more )
Specimen
S1B WT rostral to caudal 1:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
S1B WT rostral to caudal 2:
postnatal adult
(more )
Specimen
S1B WT rostral to caudal 2:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
S1B WT rostral to caudal 3:
postnatal adult
(more )
Specimen
S1B WT rostral to caudal 3:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
S1B WT rostral to caudal 4:
postnatal adult
(more )
Specimen
S1B WT rostral to caudal 4:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
S1B KO rostral to caudal 1:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: midbrain |
midbrain dopaminergic neuron |
Present |
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S1B KO 1
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Similar as in the wild-type.
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Specimen
S1B KO rostral to caudal 2:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: midbrain |
midbrain dopaminergic neuron |
Present |
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S1B KO 2
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Similar as in the wild-type.
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Specimen
S1B KO rostral to caudal 3:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: midbrain |
midbrain dopaminergic neuron |
Present |
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S1B KO 3
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Similar as in the wild-type.
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Specimen
S1B KO rostral to caudal 4:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
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Mutant Allele(s):
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Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: midbrain |
midbrain dopaminergic neuron |
Present |
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S1B KO 4
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Similar as in the wild-type.
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Analysis Tools