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Gene Expression Data
Assay Details
Assay
Reference: J:240101 Lv J, et al., 5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival. J Exp Med. 2017 Feb;214(2):529-545
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7549037
Gene symbol: Tph2
Gene name: tryptophan hydroxylase 2
Antibody: anti-Tph2
Detection system: fluorescein
Results
Specimen 4F E10.5: embryonic day 10.5 (more )
Note: Double labeled: red - Tph2; green - Pecam1 (assay MGI:7549026).
Structure Level Pattern Image Note
TS17: aorta-gonad-mesonephros Present 4F E10.5

Specimen 4F E11.0: embryonic day 11.0 (more )
Note: Double labeled: red - Tph2; green - Pecam1 (assay MGI:7549026).
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 4F E11.5

Specimen 4J E10.5: embryonic day 10.5 (more )
Note: Triple labeled: white - Tph2; red - Ddc (assay MGI:7549038); green - Pecam1 (assay MGI:7549026).
Structure Level Pattern Image Note
TS17: aorta-gonad-mesonephros Present Regionally restricted 4J E10.5 Tph2 , 4J E10.5 (merged) Expression co-localized with Ddc expression in subaortic mesenchymal cells and a subset of hematopoietic cells.

Specimen 4J E11.5: embryonic day 11.0 (more )
Note: Triple labeled: white - Tph2; red - Ddc (assay MGI:7549038); green - Pecam1 (assay MGI:7549026).
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present Regionally restricted 4J E11.5 (merged) , 4J E11.5 Tph2 Expression co-localized with Ddc expression in subaortic mesenchymal cells and a subset of hematopoietic cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory