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Gene Expression Data
Assay Details
Assay
Reference: J:249803 Guerrero-Flores G, et al., Functional determination of the differentiation potential of ventral mesencephalic neural precursor cells during dopaminergic neurogenesis. Dev Biol. 2017 Sep 1;429(1):56-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7538888
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-Th
Results
Specimen E11.5: embryonic day 11.5 (more )
Note: Data not shown. Cell counts were graphed in Figure 1A.
Structure Cell Type Level Pattern Image Note
TS19: midbrain neuron Present Expression started to accumulate at E11.5 and immunopositive cell numbers grew exponentially.

Specimen E12.0: embryonic day 12.0 (more )
Note: Data not shown. Cell counts were graphed in Figure 1A.
Structure Cell Type Level Pattern Image Note
TS20: midbrain neuron Present

Specimen E12.5: embryonic day 12.5 (more )
Note: Data not shown. Cell counts were graphed in Figure 1A.
Structure Cell Type Level Pattern Image Note
TS20: midbrain neuron Present

Specimen S1A: embryonic day 12.5 (more )
Note: BrdU at E9.5. Double labeled: red - Th; green - BrdU.
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted S1A Th , S1A Merge bottom Most of the BrdU+ cells were Th+.

Specimen S1B: embryonic day 12.5 (more )
Note: BrdU at E10.5. Triple labeled: purple - Th; red - Neurog2 (assay MGI:7538897); green - BrdU.
Structure Cell Type Level Pattern Image Note
TS20: midbrain midbrain dopaminergic neuron Present S1B Merge bottom , S1B Th Few BrdU+ cells were also positive of Th. Injection of BrdU at E10.5.

Specimen S3A right: embryonic day 11.5 (more )
Note: Double labeled: green - Th; red - Neurog2 (assay MGI:7538897).
Structure Cell Type Level Pattern Image Note
TS19: midbrain neuron Present S3A right


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory