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Gene Expression Data
Assay Details
Assay
Reference: J:336175 Fuchs MAA, et al., Intact prostaglandin signaling through EP2 and EP4 receptors in stromal progenitor cells is required for normal development of the renal cortex in mice. Am J Physiol Renal Physiol. 2022 Mar 1;322(3):F295-F307
Assay type: RNA in situ
MGI Accession ID: MGI:7531044
Gene symbol: Ptgs2
Gene name: prostaglandin-endoperoxide synthase 2
Probe: Mm-Ptgs2 (518051)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope assay.
Results
Specimen 2C (top): postnatal day 9 (more )
Note: Double labeled: red - Ptgs2; green - Ren1 (assay MGI:7531042).
Structure Level Pattern Image Note
TS28: macula densa Present Regionally restricted 2C (top) Expression restricted to tubular macula densa cells in close proximity to remin-expressing cells.
Specimen 2C (middle): postnatal day 9 (more )
Note: Double labeled: red - Ptgs2; green - Pdgfrb (assay MGI:7531043).
Structure Level Pattern Image Note
TS28: renal cortex Present Regionally restricted 2C (middle) No overlap with Pdgfrb expression in renal cortex.
Specimen 2C (bottom): postnatal day 9 (more )
Note: Double labeled: red - Ptgs2; green - Pdgfrb (assay MGI:7531043).
Structure Cell Type Level Pattern Image Note
TS28: renal medullary interstitium kidney inner medulla interstitial cell Present 2C (bottom)
Specimen 5C (top): postnatal week 15 (more )
Note: Double labeled: red - Ptgs2; green - Pdgfrb (assay MGI:7531043).
Structure Level Pattern Image Note
TS28: macula densa Present 5C (top) Expression only in cells of macula densa.
Specimen 5C (bottom): postnatal week 15 (more )
Note: Double labeled: red - Ptgs2; green - Pdgfrb (assay MGI:7531043).
Structure Cell Type Level Pattern Image Note
TS28: renal medullary interstitium kidney inner medulla interstitial cell Present Regionally restricted 5C (bottom) Expression in Pdgfrb-expressing interstitial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory