About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:84372 Previtali SC, et al., Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles. J Neurosci. 2003 Jul 2;23(13):5520-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7524126
Gene symbol: Dag1
Gene name: dystroglycan 1
Results
Specimen 2B: embryonic day 18.5 (more )
Note: Double labeled: red - Dag1; green - neurofilament.
Structure Level Pattern Image Note
TS26: spinal nerve ventral root Absent 2B No expression in motor roots.
Specimen 2C: embryonic day 18.5 (more )
Note: Double labeled: red - Dag1; green - neurofilament.
Structure Level Pattern Image Note
TS26: peripheral nerve Absent 2C No expression in peripheral nerves.
Specimen 3A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: spinal nerve ventral root Present 3A Expression beginning first in motor roots.
Specimen 3C/E: postnatal day 1 (more )
Note: Double labeled: red - Dag1; green - Mbp (assay MGI:7524128).
Structure Level Pattern Image Note
TS27: spinal nerve ventral root Present 3C , 3E Expression beginning first in motor roots.
Specimen 3F: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: spinal nerve dorsal root Trace 3F Expression in sensory root.
Specimen 3H/J: postnatal day 1 (more )
Note: Double labeled: red - Dag1; green - Mbp (assay MGI:7524128).
Structure Level Pattern Image Note
TS27: spinal nerve dorsal root Trace 3H , 3J Expression in sensory root.
Specimen 3K/M: postnatal day 1 (more )
Note: Double labeled: red - Dag1; green - Mbp (assay MGI:7524128).
Structure Level Pattern Image Note
TS27: peripheral nerve Present Regionally restricted 3K , 3M Polarized, ab-axonal (ring) pattern of expression on surface of myelinating Schwann cells, and cells still negative for Mbp expression.
Specimen 4B: postnatal day 1 (more )
Note: Double labeled: red - Dag1; green - neurofilament.
Structure Cell Type Level Pattern Image Note
TS27: nerve Schwann cell Present Regionally restricted 4B Expression only in Schwann cells around single axons. No expression surrounding unsorted axons.
Specimen 4C: postnatal adult; Lama2dy-2J/Lama2dy-2J (more )
Note: Double labeled: red - Dag1; green - neurofilament.
Structure Cell Type Level Pattern Image Note
TS28: spinal nerve ventral root Schwann cell Present Regionally restricted 4C Expression only in Schwann cells around single axons. No expression surrounding unsorted axons.
Specimen 4D: postnatal adult (more )
Note: Double labeled: red - Dag1; green - neurofilament.
Structure Cell Type Level Pattern Image Note
TS28: sciatic nerve Schwann cell Present Regionally restricted 4D Expression only in Schwann cells around single axons. No expression surrounding unsorted axons.
Specimen 4E: postnatal adult; Itgb1tm1Lscd/Itgb1tm1Mll, Tg(Mpz-cre)26Mes/0 (more )
Note: Conditional mutant. Double labeled: red - Dag1; green - neurofilament.
Structure Level Pattern Image Note
TS28: sciatic nerve Present Regionally restricted 4E Expression only in Schwann cells around single axons. No expression surrounding unsorted axons.
Specimen 4H/I: postnatal day 1 (more )
Note: Triple labeled: blue - Dag1; green - Ngfr (assay MGI:7524125); red - neurofilament.
Structure Level Pattern Image Note
TS27: nerve Trace Regionally restricted 4H , 4I Expression just beginning in Schwann cells associated with single axons. No expression in surrounding bundles of axons.
Specimen 8B: embryonic day 17.5; Itgb1tm1Lscd/Itgb1tm1Mll, Tg(Mpz-cre)26Mes/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: sciatic nerve Absent 8B Expression not prematurely induced.
Specimen 8F DG: postnatal day 28; Itgb1tm1Lscd/Itgb1tm1Mll, Tg(Mpz-cre)26Mes/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal nerve ventral root Present 8F DG
Specimen 9H: postnatal adult; Lama2dy-2J/Lama2dy-2J (more )
Structure Level Pattern Image Note
TS28: spinal nerve root Present 9H
Specimen 9S: postnatal adult; Lama2dy-2J/Lama2dy-2J (more )
Structure Level Pattern Image Note
TS28: sciatic nerve Present 9S
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory