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Gene Expression Data
Assay Details
Assay
Reference: J:310864 Zainolabidin N, et al., Distinct Activities of Tfap2A and Tfap2B in the Specification of GABAergic Interneurons in the Developing Cerebellum. Front Mol Neurosci. 2017;10:281
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7520306
Gene symbol: Tfap2b
Gene name: transcription factor AP-2 beta
Antibody: anti-AP-2b
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2J/L: postnatal day 60 (more )
Note: Double labeled: green - Tfap2b; red - Pvalb (assay MGI:7520307).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum molecular layer cerebellar stellate cell Present 2J , 2L Coexpressed with Pvalb.
TS28: cerebellum molecular layer cerebellum basket cell Present 2J , 2L Coexpressed with Pvalb.
TS28: cerebellum Purkinje cell layer Purkinje cell Absent 2J , 2L Not coexpressed with Pvalb.

Specimen 2M/O: postnatal day 60 (more )
Note: Double labeled: green - Tfap2b; red - Grm2 (assay MGI:7520308).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum internal granule cell layer cerebellar Golgi cell Present Single cells 2O , 2M Coexpressed with Grm2.
TS28: cerebellum molecular layer Present 2O , 2M

Specimen 2P/R: postnatal day 60 (more )
Note: Double labeled: green - Tfap2b; red - Rbfox3 (assay MGI:7520309).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum internal granule cell layer cerebellar granule cell Absent 2P , 2R Not coexpressed with Rbfox3.
TS28: cerebellum internal granule cell layer cerebellar Golgi cell Present Single cells 2P , 2R
TS28: cerebellum molecular layer cerebellar stellate cell Present 2P , 2R
TS28: cerebellum molecular layer cerebellum basket cell Present 2P , 2R

Specimen 3E/F: embryonic day 12.5 (more )
Note: Double labeled: green - Tfap2b; red - Tfap2a (assay MGI:7520310).
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 3F , 3E Coexpressed with Tfap2a in the ventricular zone. Some Tfap2b+ cells did not express Tfap2a.
TS20: cerebellum white matter Present 3E , 3F Coexpressed with Tfap2a.

Specimen S2B: postnatal adult (more )
Note: Triple labeled: green - Tfap2b; blue - Gad1 (assay MGI:7520319); red - Map2 (assay MGI:7520320).
Structure Cell Type Level Pattern Image Note
TS28: fastigial nucleus cerebellar inhibitory GABAergic interneuron Absent S2B Tfap2B , S2B Not coexpressed with Map2 and Gad1 in medial cerebellar nucleus.

Specimen S2D: postnatal adult (more )
Note: Triple labeled: green - Tfap2b; blue - Gad1 (assay MGI:7520319); red - Map2 (assay MGI:7520320).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum interpositus nucleus cerebellar inhibitory GABAergic interneuron Absent S2D , S2D Tfap2B Not coexpressed with Map2 and Gad1.

Specimen S2F: postnatal adult (more )
Note: Triple labeled: green - Tfap2b; blue - Gad1 (assay MGI:7520319); red - Map2 (assay MGI:7520320).
Structure Cell Type Level Pattern Image Note
TS28: dentate nucleus cerebellar inhibitory GABAergic interneuron Absent S2F , S2F Tfap2B Not coexpressed with Map2 and Gad1 in lateral deep cerebellar nucleus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory