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Gene Expression Data
Assay Details
Assay
Reference: J:224892 Yan Y, et al., Prdx4 is a compartment-specific H2O2 sensor that regulates neurogenesis by controlling surface expression of GDE2. Nat Commun. 2015;6:7006
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7520155
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-C-Isl-1 protein (K5)
Detection system: Secondary antibody
Results
Specimen S3b +/y: embryonic day 13.5 (more )
Note: Double labeled: green - Isl1; red - Foxp1 (assay MGI:7520152).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord ventral horn spinal cord motor neuron Present S3b

Specimen S3e -y or -/-: embryonic day 13.5; Prdx4tm1.1Jufu/? (more )
Note: The sex of the specimen was not specified. Double labeled: green - Isl1; red - Foxp1 (assay MGI:7520152).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord ventral horn spinal cord motor neuron Present S3e Medial division of lateral motor column (LMCm, Isl1+Foxp1+) motor neurons were increased by 20%, compared with the wild-type littermates.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory