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Gene Expression Data
Assay Details
Assay
Reference: J:84706 Assimacopoulos S, et al., Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex. J Neurosci. 2003 Jul 23;23(16):6399-403
Assay type: RNA in situ
MGI Accession ID: MGI:7518932
Gene symbol: Tgfa
Gene name: transforming growth factor alpha
Probe: TGF-alpha-cDNA6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical antihem Strong 2A Curve of strong expression in viewed from lateral face of cortical primordium.
Specimen 2F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cortical antihem Present 2F Expression maintained for several days in this position.
Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 3B Expression domain lies within cortical primordium.
Specimen 3D: embryonic day 12.5 (more )
Note: Double labeled: blue - Tgfa; red - Dlx2 (assay MGI:7518938).
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3D Expression in cortical neuroepithelium in wedge-shaped territory lacking Emx1 and Dlx2 expression.
Specimen 3G: embryonic day 12.5 (more )
Note: Double labeled: blue - Tgfa; red - Sfrp2 (assay MGI:7518929).
Structure Level Pattern Image Note
TS20: cortical antihem Present 3G Expression marks most lateral margin of cortical neuroepithelium.
Specimen 4A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical antihem Present 4A
Specimen 4B: embryonic day 14.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 4B Expression lost in antihem region.
TS22: main olfactory bulb Trace 4B Authors report spot of expression likely in olfactory bulb remnant.
Specimen 4C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical antihem Present 4C
Specimen 4D: embryonic day 13.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS21: cortical antihem Present Regionally restricted 4D Expression in antihem present in mutant at E13.5 but appears dorsally displaced.
Specimen 4E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical antihem Present 4E
Specimen 4F: embryonic day 14.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 4F Expression eliminated in antihem region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory