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Gene Expression Data
Assay Details
Assay
Reference: J:215514 Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
Assay type: RNA in situ
MGI Accession ID: MGI:7518825
Gene symbol: Wnt3a
Gene name: wingless-type MMTV integration site family, member 3A
Probe: Wnt3a probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4C Dmrt5+/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical hem Present 4C Dmrt5+/+
Specimen 4C Dmrt5-/-: embryonic day 12.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Level Pattern Image Note
TS20: cortical hem Weak 4C Dmrt5-/-
Specimen S1D: embryonic day 12.5 (more )
Note: Double labeled: blue - Wnt3a; pink - Dmrta2 (assay MGI:7518810).
Structure Level Pattern Image Note
TS20: cortical hem Present S1D
Specimen S6A Dmrt5+/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present S6A left
Specimen S6A Dmrt5-/-: embryonic day 10.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Level Pattern Image Note
TS17: telencephalon Weak Regionally restricted S6A right Reduced expression was detectable in the dorsal midline of the mutant at E10.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory