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Gene Expression Data
Assay Details
Assay
Reference: J:221639 Georgas KM, et al., An illustrated anatomical ontology of the developing mouse lower urogenital tract. Development. 2015 May 15;142(10):1893-908
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7517048
Gene symbol: Trp63
Gene name: transformation related protein 63
Antibody: anti-p63 [N2C1], internal (GTX102425)
Detection system: Secondary antibody coupled to DyLight 549
Results
Specimen 4/S4 H: embryonic day 18.5 (more )
Note: Double labeled: purple - Trp63; green - Pax2 (assay MGI:7517043).
Structure Level Pattern Image Note
TS26: pelvic urethra of female Present 4/S4H
TS26: sinovaginal bulb Present 4/S4H
Specimen 5M: postnatal adult (more )
Note: Double labeled: purple - Trp63; green - Upk3a (assay MGI:7517059).
Structure Cell Type Level Pattern Image Note
TS28: urothelium of bladder fundus bladder urothelial cell Present 5M
TS28: urothelium of bladder trigone bladder urothelial cell Present 5M
TS28: urothelium of ventral bladder neck bladder urothelial cell Present 5M
TS28: urethral gland of pelvic urethra of female Present 5M Located close to the bladder-pelvic urethra boundary.
TS28: epithelium of pelvic urethra of female epithelial cell of urethra Present 5M
TS28: epithelium of bladder-urethra transition zone Present 5M
Specimen 5N: postnatal adult (more )
Note: Double labeled: purple - Trp63; green - Upk3a (assay MGI:7517059).
Structure Cell Type Level Pattern Image Note
TS28: urothelium of bladder trigone bladder urothelial cell Present 5N
TS28: urothelium of ventral bladder neck bladder urothelial cell Present 5N
TS28: urethral gland of pelvic urethra of female Present 5N Located close to the bladder-pelvic urethra boundary.
TS28: epithelium of bladder-urethra transition zone Present 5N
TS28: epithelium of pelvic urethra of female epithelial cell of urethra Present 5N
Specimen 8G: embryonic day 12.0 (more )
Note: Double labeled: purple - Trp63; green - Krt5 (assay MGI:7517067).
Structure Level Pattern Image Note
TS20: caudal urogenital sinus epithelium Present 8G Strongest expression.
TS20: urothelium of primitive bladder Present 8G
Specimen 8H: embryonic day 13.0 (more )
Note: Double labeled: purple - Trp63; green - Krt5 (assay MGI:7517067).
Structure Cell Type Level Pattern Image Note
TS21: urothelium of primitive bladder Present 8H
TS21: epithelium of pelvic urethra epithelial cell of urethra Present 8H Strongest expression.
Specimen 8I: embryonic day 13.0 (more )
Note: Double labeled: purple - Trp63; green - Krt5 (assay MGI:7517067).
Structure Cell Type Level Pattern Image Note
TS21: epithelium of pelvic urethra epithelial cell of urethra Present 8I
Specimen 8J: embryonic day 14.0 (more )
Note: Double labeled: purple - Trp63; green - Krt5 (assay MGI:7517067).
Structure Cell Type Level Pattern Image Note
TS22: urothelium of bladder bladder urothelial cell Present 8J
TS22: epithelium of pelvic urethra epithelial cell of urethra Present 8J
Specimen 8K: embryonic day 14.0 (more )
Note: Double labeled: purple - Trp63; green - Krt5 (assay MGI:7517067).
Structure Cell Type Level Pattern Image Note
TS22: epithelium of pelvic urethra epithelial cell of urethra Present Regionally restricted 8K No expression in the superficial cell layer.
Specimen 8L: embryonic day 16.0 (more )
Note: Double labeled: purple - Trp63; green - Krt5 (assay MGI:7517067).
Structure Cell Type Level Pattern Image Note
TS24: basal cell layer of bladder urothelium bladder urothelial cell Present 8L Coexpressed with Krt5.
Specimen 8M: embryonic day 16.0 (more )
Note: Double labeled: purple - Trp63; green - Upk3a (assay MGI:7517059).
Structure Cell Type Level Pattern Image Note
TS24: basal cell layer of bladder urothelium bladder urothelial cell Present 8M
TS24: intermediate cell layer of bladder urothelium bladder urothelial cell Present 8M
Specimen 8S: embryonic day 17.0 (more )
Note: Triple labeled: purple - Trp63; red - Krt14 (assay MGI:7517085); green - Krt5 (assay MGI:7517067).
Structure Cell Type Level Pattern Image Note
TS25: urothelium of bladder fundus bladder urothelial cell Present 8S upper
TS25: urothelium of bladder trigone bladder urothelial cell Present 8S upper
TS25: urothelium of ventral bladder neck bladder urothelial cell Present 8S upper
TS25: epithelium of pelvic urethra of male epithelial cell of urethra Present 8S upper
Specimen 8U: embryonic day 17.0 (more )
Note: Double labeled: purple - Trp63; green - Foxa2 (assay MGI:7517084).
Structure Cell Type Level Pattern Image Note
TS25: basal cell layer of bladder urothelium bladder urothelial cell Present 8U Trp63 , 8U Foxa2/Trp63
TS25: intermediate cell layer of bladder urothelium bladder urothelial cell Present 8U Trp63 , 8U Foxa2/Trp63
TS25: urothelium of bladder trigone bladder urothelial cell Present 8U Trp63 , 8U Foxa2/Trp63
Specimen 8V: embryonic day 17.0 (more )
Note: Triple labeled: purple - Trp63; red - Krt13 (assay MGI:7517082); green - Upk3a (assay MGI:7517059).
Structure Cell Type Level Pattern Image Note
TS25: urothelium of bladder fundus bladder urothelial cell Present 8V
TS25: urothelium of bladder trigone bladder urothelial cell Present 8V
TS25: urothelium of ventral bladder neck bladder urothelial cell Present 8V
TS25: epithelium of pelvic urethra of male epithelial cell of urethra Present 8V
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory