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Gene Expression Data
Assay Details
Assay
Reference: J:309396 Silva-Alvarez C, et al., Apical Polarization of SVCT2 in Apical Radial Glial Cells and Progenitors During Brain Development. Mol Neurobiol. 2017 Sep;54(7):5449-5467
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7516178
Gene symbol: Slc23a2
Gene name: solute carrier family 23 (nucleobase transporters), member 2
Antibody: anti-SVCT2 (G-19)
Detection system: Secondary antibody coupled to Cy2
Results
Specimen 3A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon marginal layer Absent 3A
TS18: telencephalon ventricular layer Absent 3A
Specimen 3B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Widespread 3B Expressed over the whole thickness of the cortical sheet with particular intensity toward the ventricular border.
Specimen 3G/I: embryonic day 13.0 (more )
Note: Double labeled: green - Slc23a2; red - Tubb3 (assay MGI:7516181).
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex Present 3G , 3I
TS21: cortical plate neuron of the forebrain Weak 3G , 3I Coexpressed with Tubb3.
Specimen 4A/F/G/I: embryonic day 15.0 (more )
Note: Triple labeled: green - Slc23a2; red - Pcna (assay MGI:7516179); blue - Phgdh (assay MGI:7516182).
Structure Cell Type Level Pattern Image Note
TS23: cerebral cortex ventricular layer forebrain radial glial cell Strong Regionally restricted 4I , 4F , 4A Coexpressed with Phgdh strongly in the ventricular rim.
TS23: telencephalon meninges Strong 4A , 4I , 4G , 4F
TS23: cerebral cortex subventricular zone forebrain radial glial cell Present 4I , 4A , 4F , 4G Coexpressed with Phgdh, not Pcna.
Specimen 4J/M: embryonic day 15.0 (more )
Note: Triple labeled: green - Slc23a2; red - Pcna (assay MGI:7516179); blue - Phgdh (assay MGI:7516182).
Structure Level Pattern Image Note
TS23: brainstem Present 4J , 4M Coexpressed with Phgdh and Pcna in the ventricular border of the IV ventricle.
TS23: cerebellum ventricular layer Present 4J , 4M Coexpressed with Phgdh and Pcna in the ventricular border of the IV ventricle.
TS23: choroid plexus Present 4J , 4M Coexpressed with Phgdh and Pcna in the ventricular border of the IV ventricle.
TS23: cerebellum layer Present Regionally restricted 4J , 4M Coexpressed with Phgdh and Pcna in the external cerebellar area.
Specimen 6A/C: embryonic day 18.0 (more )
Note: Double labeled: green - Slc23a2; red - Tubb3 (assay MGI:7516181).
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Present Regionally restricted 6C , 6A Predominant expression in the ventricular border.
TS26: cortical subplate Present 6C , 6A
Specimen 6D/F: embryonic day 18.0 (more )
Note: Double labeled: green - Slc23a2; red - Tubb3 (assay MGI:7516181).
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Present 6F , 6D Predominant expression in the ventricular border.
Specimen 6G/I: embryonic day 18.0 (more )
Note: Double labeled: green - Slc23a2; red - Tubb3 (assay MGI:7516181).
Structure Level Pattern Image Note
TS26: cerebral cortex marginal zone Present 6G , 6I Expressed in both neuronal bodies and processes.
TS26: cortical plate Present 6G , 6I Expressed in both neuronal bodies and processes.
TS26: cortical subplate Present 6G , 6I Expressed in both neuronal bodies and processes.
Specimen 6J: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Weak 6J
TS26: choroid plexus Strong 6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory