Sycp1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:256987 Shi B, et al., MORC2B is essential for meiotic progression and fertility. PLoS Genet. 2018 Jan;14(1):e1007175
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7509244
Gene symbol:	Sycp1
Gene name:	synaptonemal complex protein 1

Antibody:	Anti-Scp1 (Ab-15090)
Detection system:	Secondary antibody coupled to fluorescein

Results

4A +/+ ©

Specimen 4A SYCP1 +/+: postnatal (more

)
Note: Double labeled: green - Sycp1; red - Sycp2 (assay MGI:7509245).

Structure	Level	Pattern	Image	Note
TS28: spermatocyte	Present		4A +/+	Spermatocytes contain fully synapsed autosomes.

4A -/- ©

Specimen 4A SYCP1 -/-: postnatal; Morc2b^tm1Jw/Morc2b^tm1Jw (more

)
Note: Double labeled: green - Sycp1; red - Sycp2 (assay MGI:7509245).

Structure	Level	Pattern	Image	Note
TS28: spermatocyte	Absent		4A -/-	Spermatocytes lack full chromosomal synapsis.

4B +/+ ©

Specimen 4B SYCP1 +/+: embryonic day 17.5 (more

)
Note: Double labeled: green - Sycp1; red - Sycp2 (assay MGI:7509245).

Structure	Level	Pattern	Image	Note
TS25: oocyte	Present		4B +/+	Oocytes with fully synapsed chromosome pairs.

4B -/- ©

Specimen 4B SYCP1 -/-: embryonic day 17.5; Morc2b^tm1Jw/Morc2b^tm1Jw (more

)
Note: Double labeled: green - Sycp1; red - Sycp2 (assay MGI:7509245).

Structure	Level	Pattern	Image	Note
TS25: ovary	Absent		4B -/-	Pachytene stage oocytes are absent.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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