About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:276652 Fang Q, et al., Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 Mar 4;9(1):3357
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7506985
Gene symbol: Cfl1
Gene name: cofilin 1, non-muscle
Antibody: anti-p-cofilin (hSer3)-R (sc-12912)
Assay notes: Fixation with 4% polyoxymethylene.
Results
Specimen 6c p-cofilin WT: postnatal day 30 (more )
Note: Double labeled: red - Cfl1 (p-cofilin); green - Myo7a (assay MGI:7506974).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlea auditory hair cell Present 6c p-cofilin WT , 6c Merged WT (lower) No difference in expression from apical to basal turns.
Specimen 6c p-cofilin DKO: postnatal day 30; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Cfl1 (p-cofilin); green - Myo7a (assay MGI:7506974).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlea auditory hair cell Weak 6c p-cofilin DKO , 6c Merged DKO (lower) Expression signifiantly decreased compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory