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Gene Expression Data
Assay Details
Assay
Reference: J:249826 Tanabe Y, et al., IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2alpha. Nat Commun. 2017 Sep 01;8(1):408
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7506608
Gene symbol: Slc32a1
Gene name: solute carrier family 32 (GABA vesicular transporter), member 1
Antibody: anti-VGAT (131 003)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5a VGAT Dorsal CA1 Igsf21+/+: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 5a VGAT Igsf21+/+ S. pyr. , 5a VGAT Igsf21+/+(upper)
TS28: CA1 stratum radiatum Present 5a VGAT Igsf21+/+(upper) , 5a VGAT Igsf21+/+ S. rad.
Specimen 5a VGAT Dorsal CA1 Igsf21-/-: postnatal week 4; Igsf21tm2a(EUCOMM)Hmgu/Igsf21tm2a(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 5a VGAT Igsf21-/- (upper) , 5a VGAT Igsf21-/- S. pyr. Expression unchanged compared to wild type.
TS28: CA1 stratum radiatum Weak 5a VGAT Igsf21-/- S. rad. , 5a VGAT Igsf21-/- (upper) Expression 20% lower compared to wild type.
Specimen 5d VGAT Ventral CA1 Igsf21+/+: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 5d VGAT Igsf21+/+ S. pyr. , 5d VGAT Igsf21+/+ (upper)
TS28: CA1 stratum radiatum Present 5d VGAT Igsf21+/+ (upper) , 5d VGAT Igsf21+/+ S. rad.
Specimen 5d VGAT Ventral CA1 Igsf21-/-: postnatal week 4; Igsf21tm2a(EUCOMM)Hmgu/Igsf21tm2a(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 5d VGAT Igsf21-/- S. pyr. , 5d VGAT Igsf21-/- (upper) Expression unchanged compared to wild type.
TS28: CA1 stratum radiatum Weak 5d VGAT Igsf21-/- (upper) , 5d VGAT Igsf21-/- S. rad. Expression 20% lower compared to wild type.
Specimen S9a VGAT Igsf21+/+: postnatal week 4 (more )
Note: Double labeled: green - Slc32a1 (VGAT); red - Gphn (assay MGI:7506612).
Structure Level Pattern Image Note
TS28: cortical layer V Present S9a Igsf21+/+ VGAT , S9a Igsf21+/+ (merged)
TS28: somatosensory cortex Present S9a Igsf21+/+ VGAT , S9a Igsf21+/+ (merged)
Specimen S9a VGAT Igsf21-/-: postnatal week 4; Igsf21tm2a(EUCOMM)Hmgu/Igsf21tm2a(EUCOMM)Hmgu (more )
Note: Double labeled: green - Slc32a1 (VGAT); red - Gphn (assay MGI:7506612).
Structure Level Pattern Image Note
TS28: cortical layer V Weak S9a Igsf21-/- (merged) , S9a Igsf21-/- VGAT Expression significantly decreased compared to wild type.
TS28: somatosensory cortex Weak S9a Igsf21-/- (merged) , S9a Igsf21-/- VGAT Expression significantly decreased compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory