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Gene Expression Data
Assay Details
Assay
Reference: J:143047 Kanatani S, et al., COUP-TFII is preferentially expressed in the caudal ganglionic eminence and is involved in the caudal migratory stream. J Neurosci. 2008 Dec 10;28(50):13582-91
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7505596
Gene symbol: Calb1
Gene name: calbindin 1
Antibody: anti-Calbindin D28k (CB-38), rabbit
Detection system: Secondary antibody coupled to rhodamine
Results
Specimen 3A/C: embryonic day 13.5 (more )
Note: Double labeled: magenta - Calb1; green - Nr2f2 (assay MGI:7505588).
Structure Cell Type Level Pattern Image Note
TS21: telencephalon neuron of the forebrain Present Regionally restricted 3L , 3H , 3K , 3A , 3J , 3G , 3D , 3C , 3N , 3E Expression was detected in a migratory stream from the caudal ganglionic eminence to the caudal cortex and hippocampus. A majority of the migrating neurons were positive for both Nr2f2 and Calb1 (71% of the Calb1 cells).
TS21: caudal ganglionic eminence neuron of the forebrain Present 3A , 3G , 3D , 3C , 3E
TS21: cerebral cortex neuron of the forebrain Present Regionally restricted 3K , 3N , 3A , 3J , 3L , 3H , 3C Expression was detected in the caudal cortex. A large population (56.8%) of Calb1+ migrating cells continued to express a lower level of Nr2f2.

Specimen 6A/C: embryonic day 13.5 (more )
Note: Double labeled: magenta - Calb1; green - Nr2f2 (assay MGI:7505588).
Structure Level Pattern Image Note
TS21: caudal ganglionic eminence Present Non-Uniform 6I , 6G , 6F , 6D , 6C , 6A Two cohorts of Calb1 immunopositive cells were identified. A caudal population co-labeled with Nr2f2 (64.4% of cells), and a rostral population that tended to be Nr2f2-negative (only 14.4% of cells were co-labeled).

Specimen S2A: embryonic day 15.5 (more )
Note: Double labeled: magenta - Calb1; green - Nr2f2 (assay MGI:7505588).
Structure Level Pattern Image Note
TS23: cerebral cortex Present Regionally restricted S2A , S2D , S2B A large portion of Calb1+ cells in the caudal cortex co-stain weakly for Nr2f2.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory