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Gene Expression Data
Assay Details
Assay
Reference: J:335425 Derbyshire ML, et al., Loss of Tbx3 in Mouse Eye Causes Retinal Angiogenesis Defects Reminiscent of Human Disease. Invest Ophthalmol Vis Sci. 2023 May 1;64(5):1
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482273
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti PAX6 (DSHB)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 1L: postnatal day 2; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax6; green - Tbx3 reporter (assay MGI:7482268).
Structure Cell Type Level Pattern Image Note
TS27: retina ganglion cell layer retinal ganglion cell Present 1L (merge) , 1L Pax6
Specimen S2G: postnatal day 7; Tbx3tm3.1Moon/Tbx3+ (more )
Structure Cell Type Level Pattern Image Note
TS28: retina inner nuclear layer amacrine cell Present S2G Pax6 , S2G Pax6/GFP
TS28: retina inner nuclear layer Mueller cell Present S2G Pax6 , S2G Pax6/GFP
TS28: retina ganglion cell layer retinal ganglion cell Present S2G Pax6 , S2G Pax6/GFP
Specimen S2H: postnatal day 7; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax6; green - Tbx3 reporter (assay MGI:7482268).
Structure Cell Type Level Pattern Image Note
TS28: retina inner nuclear layer amacrine cell Present S2H Pax6 , S2H Pax6/GFP
TS28: retina inner nuclear layer Mueller cell Present S2H Pax6 , S2H Pax6/GFP
TS28: retina ganglion cell layer retinal ganglion cell Present S2H Pax6/GFP , S2H Pax6
Specimen S2I: postnatal day 14; Tbx3tm3.1Moon/Tbx3+ (more )
Structure Cell Type Level Pattern Image Note
TS28: retina inner nuclear layer amacrine cell Present S2I Pax6 , S2I Pax6/GFP
TS28: retina inner nuclear layer Mueller cell Present S2I Pax6 , S2I Pax6/GFP
Specimen S2J: postnatal day 14; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax6; green - Tbx3 reporter (assay MGI:7482268).
Structure Cell Type Level Pattern Image Note
TS28: retina inner nuclear layer amacrine cell Present S2J' Pax6 , S2J Pax6 , S2J Pax6/GFP , S2J' Pax6/GFP
TS28: retina inner nuclear layer Mueller cell Present S2J' Pax6 , S2J Pax6 , S2J Pax6/GFP , S2J' Pax6/GFP
TS28: retina ganglion cell layer retinal ganglion cell Present S2J' Pax6/GFP , S2J' Pax6 , S2J Pax6/GFP , S2J Pax6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory