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Gene Expression Data
Assay Details
Assay
Reference: J:207609 Hilliard SA, et al., Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7481346
Gene symbol: Pcna
Gene name: proliferating cell nuclear antigen
Antibody: anti-PCNA
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 9A: embryonic day 14.5 (more )
Note: Double labeled: green - Pcna; red - Six2 (assay MGI:7481327).
Structure Level Pattern Image Note
TS22: renal cortical interstitium Present 9A
Specimen 9B: embryonic day 14.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: green - Pcna; red - Six2 (assay MGI:7481327).
Structure Level Pattern Image Note
TS22: renal cortical interstitium Present 9B The stroma dorsal to the thinning cap underwent increased proliferation regionally in the mutant kidneys.
Specimen 9C: embryonic day 14.5 (more )
Note: Double labeled: green - Pcna; red - Six2 (assay MGI:7481327).
Structure Level Pattern Image Note
TS22: renal cortical interstitium Present 9C
Specimen 9D: embryonic day 14.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: green - Pcna; red - Six2 (assay MGI:7481327).
Structure Level Pattern Image Note
TS22: renal cortical interstitium Present 9D The stroma dorsal to the thinning cap underwent increased proliferation regionally in the mutant kidneys.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory