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Gene Expression Data
Assay Details
Assay
Reference: J:207609 Hilliard SA, et al., Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7481339
Gene symbol: H2ax
Gene name: H2A.X variant histone
Antibody: anti-gamma H2A.X (phospho S139) (abcam; ab11174)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4E: embryonic day 14.5 (more )
Note: Double labeled: green - H2ax; red - Six2 (assay MGI:7481327).
Structure Level Pattern Image Note
TS22: metanephros Present 4E Not coexpressed with Six2.

Specimen 4F: embryonic day 14.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: green - H2ax; red - Six2 (assay MGI:7481327).
Structure Level Pattern Image Note
TS22: cap mesenchyme Present 4F There were cells coexpressed with Six2.

Specimen 4G: embryonic day 14.5 (more )
Note: Double labeled: green - H2ax; red - Six2 (assay MGI:7481327).
Structure Level Pattern Image Note
TS22: metanephros Present 4G Not coexpressed with Six2.

Specimen 4H: embryonic day 14.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: green - H2ax; red - Six2 (assay MGI:7481327).
Structure Level Pattern Image Note
TS22: cap mesenchyme Present 4H There were cells coexpressed with Six2.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory