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Gene Expression Data
Assay Details
Assay
Reference: J:249296 Spiller CM, et al., Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7467396
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67 (TEC-3; M7249)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3E: embryonic day 14.5; Rb1tm1.2Gfk/Rb1+ (more )
Note: Double labeled: red - Mki67; green - Ddx4 (assay MGI:7467392).
Structure Level Pattern Image Note
TS22: germ cell of testis Absent 3E In wild type the cells have stopped proliferating and entered cell cycle arrest.
Specimen 3F: embryonic day 14.5; Rb1tm1.2Gfk/Rb1tm1.2Gfk (more )
Note: Double labeled: red - Mki67; green - Ddx4 (assay MGI:7467392).
Structure Level Pattern Image Note
TS22: germ cell of testis Present 3F In the mutant 4% (a significant number) of the germ cells are still proliferating.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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