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Gene Expression Data
Assay Details
Assay
Reference: J:202344 Lesko MH, et al., Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7447380
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Detection system: Secondary antibody
Results
Specimen 3A: embryonic day 16.5; Sox2tm4.1Skn/Sox2tm4.1Skn (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Level Pattern Image Note
TS24: hair follicle dermal papilla Present 3A

Specimen 3B: embryonic day 16.5; Sox2tm4.1Skn/Sox2tm4.1Skn, Tg(Prdm1-cre)1Masu/0 (more )
Note: Conditional mutant. Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Level Pattern Image Note
TS24: hair follicle dermal papilla Absent 3B

Specimen 3C: embryonic day 16.5; Sox2tm4.1Skn/Sox2tm4.1Skn (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Level Pattern Image Note
TS24: hair follicle dermal papilla Present 3C

Specimen 3D: embryonic day 16.5; Sox2tm4.1Skn/Sox2tm4.1Skn, Tg(Prdm1-cre)1Masu/0 (more )
Note: Conditional mutant. Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Level Pattern Image Note
TS24: hair follicle dermal papilla Absent 3D

Specimen 3K: postnatal day 2; Sox2tm4.1Skn/Sox2tm4.1Skn (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Level Pattern Image Note
TS27: hair follicle dermal papilla Present 3K

Specimen 3L: postnatal day 2; Sox2tm4.1Skn/Sox2tm4.1Skn, Tg(Prdm1-cre)1Masu/0 (more )
Note: Conditional mutant. Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Level Pattern Image Note
TS27: hair follicle dermal papilla Absent 3L

Specimen 3M: postnatal day 2; Sox2tm4.1Skn/Sox2tm4.1Skn (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Level Pattern Image Note
TS27: hair follicle dermal papilla Present 3M

Specimen 3N: postnatal day 2; Sox2tm4.1Skn/Sox2tm4.1Skn, Tg(Prdm1-cre)1Masu/0 (more )
Note: Conditional mutant. Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Level Pattern Image Note
TS27: hair follicle dermal papilla Absent 3N

Specimen 5C: embryonic day 14.5 (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Cell Type Level Pattern Image Note
TS22: epidermis basal layer Merkel cell Present 5C

Specimen 5D: embryonic day 16.5 (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Cell Type Level Pattern Image Note
TS24: epidermis basal layer Merkel cell Present 5D

Specimen 5E: embryonic day 18.5 (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer Merkel cell Present 5E

Specimen 5G: embryonic day 16.5 (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Cell Type Level Pattern Image Note
TS24: epidermis basal layer Merkel cell Present Regionally restricted 5G Expressed around the guard hairs, not found in association with awl/auchene or zigzag hairs.

Specimen 5H: embryonic day 16.5 (more )
Note: Double labeled: green - Sox2; red - Krt14 (assay MGI:7447381).
Structure Cell Type Level Pattern Image Note
TS24: hair follicle dermal papilla Present 5H
TS24: epidermis basal layer Merkel cell Present 5H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory