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Gene Expression Data
Assay Details
Assay
Reference: J:75868 Lu QR, et al., Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection. Cell. 2002 Apr 5;109(1):75-86
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7432594
Gene symbol: Vsx2
Gene name: visual system homeobox 2
Antibody: anti-Chx10
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5A +/+ E10.5: embryonic day 10.5 (more )
Note: Double labeled: red - Vsx2; green - Isl1 (assay MGI:7432592).
Structure Cell Type Level Pattern Image Note
TS17: neural tube lateral wall spinal cord interneuron Present Regionally restricted 5A +/+ left Expressed in the V2 interneurons.
Specimen 5A -/- E10.5: embryonic day 10.5; Olig2tm1Rth/Olig2tm1Rth (more )
Note: Double labeled: red - Vsx2; green - Isl1 (assay MGI:7432592).
Structure Cell Type Level Pattern Image Note
TS17: neural tube lateral wall spinal cord interneuron Present Regionally restricted 5A -/- left Increased expression in the V2 interneurons, which also expanded ventrally into the motor neuron domain.
Specimen 5A +/+ E12.5: embryonic day 12.5 (more )
Note: Double labeled: red - Vsx2; green - Lhx3 (assay MGI:7432593).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord lateral wall spinal cord interneuron Present Regionally restricted 5A +/+ middle Expressed in the V2 interneurons.
Specimen 5A -/- E12.5: embryonic day 12.5; Olig2tm1Rth/Olig2tm1Rth (more )
Note: Double labeled: red - Vsx2; green - Lhx3 (assay MGI:7432593).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord lateral wall spinal cord interneuron Present Regionally restricted 5A -/- middle Increased expression in the V2 interneurons, which also expanded ventrally into the motor neuron domain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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