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Gene Expression Data
Assay Details
Assay
Reference: J:268254 Rich CA, et al., Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427364
Gene symbol: Omp
Gene name: olfactory marker protein
Antibody: Anti-OMP (Wako)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4a: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Triple labeled: green - Omp; magenta - Prph (assay MGI:7427372); cyan - Tubb3 (assay MGI:7427401).
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve Present 4a , 4b1 , 4b2
TS24: main olfactory bulb olfactory nerve layer Present Widespread 4c2 , 4b1 , 4c1 , 4b2 , 4a
TS24: main olfactory bulb external plexiform layer Absent 4c1 , 4a , 4b1 , 4c2 , 4b2
TS24: olfactory epithelium olfactory receptor cell Present 4a Expression is seen in mature olfactory receptor neurons.
Specimen 4d: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Triple labeled: green - Omp; magenta - Prph (assay MGI:7427372); cyan - Tubb3 (assay MGI:7427401).
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve Present 4e1 , 4d , 4e2
TS24: main olfactory bulb olfactory nerve layer Present Widespread 4f2 , 4f1 , 4e1 , 4d , 4e2 The ONL is thinner in the null compared to the heterozygote.
TS24: main olfactory bulb external plexiform layer Absent 4f1 , 4e1 , 4f2 , 4e2 , 4d
TS24: olfactory epithelium olfactory receptor cell Present 4d Expression is seen in mature olfactory receptor neurons. Their number is reduced in the null compared to the heterozygote.
Specimen 5a: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5a
Specimen 5b: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5b
Specimen 5c: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5c
Specimen 5d: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5d
Specimen 5e: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5e
Specimen 5f: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5f
Specimen 5g: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5g
Specimen 5k: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5k The ONL volume is significantly reduced in the null compared to the heterozygote.
Specimen 5l: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5l The ONL volume is significantly reduced in the null compared to the heterozygote.
Specimen 5m: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5m The ONL volume is significantly reduced in the null compared to the heterozygote.
Specimen 5n: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5n The ONL volume is significantly reduced in the null compared to the heterozygote.
Specimen 5o: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5o The ONL volume is significantly reduced in the null compared to the heterozygote.
Specimen 5p: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5p The ONL volume is significantly reduced in the null compared to the heterozygote.
Specimen 5q: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer Present Widespread 5q The ONL volume is significantly reduced in the null compared to the heterozygote.
Specimen 6a: embryonic day 16.5; Frzbtm1.1Fplu/Frzb+ (more )
Note: Coronal section. Double labeled: green - Omp; magenta - Tubb3 (assay MGI:7427402).
Structure Cell Type Level Pattern Image Note
TS24: olfactory epithelium olfactory receptor cell Present 6a , 6g Expression is seen in mature olfactory receptor neurons.
Specimen 6b: embryonic day 16.5; Frzbtm1.1Fplu/Frzbtm1.1Fplu (more )
Note: Coronal section. Double labeled: green - Omp; magenta - Tubb3 (assay MGI:7427402).
Structure Cell Type Level Pattern Image Note
TS24: olfactory epithelium olfactory receptor cell Present 6h , 6b Expression is seen in mature olfactory receptor neurons. Their number is significantly reduced in the null compared to the heterozygote.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory