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Gene Expression Data
Assay Details
Assay
Reference: J:235650 Mao H, et al., Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly. PLoS Genet. 2016 Sep;12(9):e1006282
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7425183
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tuj1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2H: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+ (more )
Structure Level Pattern Image Note
TS20: neocortex Present Regionally restricted 2H Expression in neuronal layer.
Specimen 2J: embryonic day 12.5; Eif4a3tm1.1Dlsi/Eif4a3+, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present Regionally restricted 2J Increase in thickness of neuronal layer.
Specimen 2R,2T: embryonic day 12.5; Eif4a3tm1.1Dlsi/Eif4a3+, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Tuj1 (Tubb3); red - CC3 (Casp3 assay MGI:7425184).
Structure Level Pattern Image Note
TS20: neocortex Present 2T , 2R
Specimen 2W: embryonic day 14.5; Emx1tm1(cre)Krj/Emx1+ (more )
Structure Level Pattern Image Note
TS22: neocortex Present 2W
Specimen 2X: embryonic day 14.5; Eif4a3tm1.1Dlsi/Eif4a3+, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: neocortex Present 2X
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory