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Gene Expression Data
Assay Details
Assay
Reference: J:104307 Wilson ME, et al., The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7408288
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Reporter: lacZ
Direct Detection
Assay notes: Fixative was 2% paraformaldehyde and 0.1% glutaraldehyde and post-fixed in 4% paraformaldehyde.
Results
Specimen 2A: embryonic day 9.5; Sox2tm1Rlb/Sox2+ (more )
Structure Level Pattern Image Note
TS15: foregut Strong 2A Expression is stronger in the developing stomach.
TS15: midgut Weak Regionally restricted 2A Expression is in the proximal midgut.
TS15: pancreas primordium Absent 2A

Specimen 2B: embryonic day 9.5; Sox2tm1Rlb/Sox2+ (more )
Note: Double labeled: blue - Sox2 reporter; brown - Pdx1 (assay MGI:7408289).
Structure Level Pattern Image Note
TS15: foregut Present 2B
TS15: midgut Weak Regionally restricted 2B Expression is in the proximal midgut.
TS15: pancreas primordium Absent 2B

Specimen not shown E10.5: embryonic day 10.5; Sox2tm1Rlb/Sox2+ (more )
Structure Level Pattern Image Note
TS17: foregut Weak
TS17: pancreas primordium Absent

Specimen not shown E16.5: embryonic day 16.5; Sox2tm1Rlb/Sox2+ (more )
Structure Level Pattern Image Note
TS24: gut epithelium Absent
TS24: pancreas Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory