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Gene Expression Data
Assay Details
Assay
Reference: J:252045 Cubillos-Rojas M, et al., The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination. Oncotarget. 2016 Aug 30;7(35):56083-56106
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7335055
Gene symbol: Calb1
Gene name: calbindin 1
Antibody: clone CB-955 (#C9848)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 9A: postnatal week 9 (more )
Note: Double labeled: red - Calb1; green - Herc2 (assay MGI:7335056).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Present 9A middle , 9A right
Specimen 9B: postnatal week 9 (more )
Note: Double labeled: red - Calb1; green - Herc2 (assay MGI:7335056).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Present 9B right , 9B middle
Specimen 9C: postnatal week 9; Herc2Gt(AR0530)Wtsi/Herc2+ (more )
Note: Double labeled: red - Calb1; green - Herc2 (assay MGI:7335056).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Present Regionally restricted 9C middle , 9C right Parasagittal bands of Purkinje cells loss in the vermis and paravermal zones and areas of extensive Purkinje cell loss in the cerebellar paraflocculus.
Specimen 9D: postnatal week 9; Herc2Gt(AR0530)Wtsi/Herc2+ (more )
Note: Double labeled: red - Calb1; green - Herc2 (assay MGI:7335056).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Present Regionally restricted 9D middle , 9D right Parasagittal bands of Purkinje cells loss in the vermis and paravermal zones.
Specimen 9E: postnatal week 9; Herc2Gt(AR0530)Wtsi/Herc2+ (more )
Note: Double labeled: red - Calb1; green - Herc2 (assay MGI:7335056).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Present Regionally restricted 9E right , 9E middle Extensive Purkinje cell loss in the cerebellar paraflocculus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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