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Gene Expression Data
Assay Details
Assay
Reference: J:216287 Czajkowski MT, et al., Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle. Dev Biol. 2014 Nov 15;395(2):307-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7331539
Gene symbol: Myod1
Gene name: myogenic differentiation 1
Antibody: anti-MyoD
Detection system: Secondary antibody
Results
Specimen 3A: embryonic day 10.5; Dll1+/Dll1tm2Gos (more )
Note: Double labeled: green - Myod1; red - Des (assay MGI:7331538).
Structure Cell Type Level Pattern Image Note
TS17: branchial arch mesenchyme skeletal muscle myoblast Present Regionally restricted 3A , 3A lower right Expressed in the branchiomeric muscle.
TS17: pharynx mesenchyme Absent 3A
Specimen 3B: embryonic day 10.5; Dll1tm1Gos/Dll1tm2Gos (more )
Note: Double labeled: green - Myod1; red - Des (assay MGI:7331538).
Structure Cell Type Level Pattern Image Note
TS17: branchial arch mesenchyme skeletal muscle myoblast Present Regionally restricted 3B , 3B lower right Increased expression in the branchiomeric muscle (quantified in 3C).
TS17: pharynx mesenchyme Absent 3B
Specimen 3D: embryonic day 11.5; Dll1+/Dll1tm2Gos (more )
Note: Double labeled: green - Myod1; red - Des (assay MGI:7331538).
Structure Cell Type Level Pattern Image Note
TS19: branchial arch mesenchyme skeletal muscle myoblast Present Regionally restricted 3D lower right , 3D Expressed in the branchiomeric muscle.
TS19: occipital myotome skeletal muscle myoblast Present 3D tongue muscle
Specimen 3E: embryonic day 11.5; Dll1tm1Gos/Dll1tm2Gos (more )
Note: Double labeled: green - Myod1; red - Des (assay MGI:7331538).
Structure Cell Type Level Pattern Image Note
TS19: branchial arch mesenchyme skeletal muscle myoblast Present Regionally restricted 3E lower right , 3E Expressed in the branchiomeric muscle, similar as in the control (quantified in 3F).
TS19: occipital myotome skeletal muscle myoblast Present 3E Increased expression in the tongue muscle (quantified in 3F).
Specimen 3G: embryonic day 15.0; Dll1+/Dll1tm2Gos (more )
Note: Double labeled: green - Myod1; red - Des (assay MGI:7331538).
Structure Cell Type Level Pattern Image Note
TS23: tongue muscle skeletal muscle myoblast Present 3G , 3G lower right
TS23: masseter skeletal muscle myoblast Present 3G branchiomeric muscles
Specimen 3H: embryonic day 15.0; Dll1tm1Gos/Dll1tm2Gos (more )
Note: Double labeled: green - Myod1; red - Des (assay MGI:7331538).
Structure Cell Type Level Pattern Image Note
TS23: tongue muscle skeletal muscle myoblast Present 3H , 3H lower right Decreased expression compared with the control (quantified in 3I), and the size of the muscle was reduced.
TS23: masseter skeletal muscle myoblast Absent 3H branchiomeric muscles
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory