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Gene Expression Data
Assay Details
Assay
Reference: J:255320 Pederick DT, et al., Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy. Neuron. 2018 Jan 3;97(1):59-66.e5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7329952
Gene symbol: Sox3
Gene name: SRY (sex determining region Y)-box 3
Antibody: anti-Sox3 (AF2569)
Detection system: Secondary antibody
Results
Specimen S3B left: embryonic day 13.5; Sox3em2Pqt/Sox3+ (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted S3B SOX3 left This cortex shows normal X-inactivation.
Specimen S3B right: embryonic day 13.5; Pcdh19tm1Tac/Pcdh19+, Sox3em2Pqt/Sox3+ (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted S3B SOX3 right This cortex shows abnormal cell sorting of positive and negative neural progenitor cells.
Specimen S3C: embryonic day 8.5; Pcdh19em1Pqt/Y (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS13: neural ectoderm Present S3C right
Specimen S3D top: embryonic day 9.5; Pcdh19em1Pqt/Y (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS15: telencephalon Present S3D top
Specimen S3D middle: embryonic day 9.5; Pcdh19em1Pqt/Pcdh19+ (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS15: telencephalon Present S3D middle
Specimen S3D bottom: embryonic day 9.5; Pcdh19tm1Tac/Pcdh19em1Pqt (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS15: telencephalon Present S3D bottom
Specimen S3E top: embryonic day 10.5; Pcdh19em1Pqt/Y (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS17: telencephalon Present S3E top
Specimen S3E middle: embryonic day 10.5; Pcdh19em1Pqt/Pcdh19+ (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS17: telencephalon Present S3E middle
Specimen S3E bottom: embryonic day 10.5; Pcdh19tm1Tac/Pcdh19em1Pqt (more )
Note: Double labeled: magenta - Sox3; green - Pcdh19 (assay MGI:7329910).
Structure Level Pattern Image Note
TS17: telencephalon Present S3E bottom
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory