About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:326355 Bademci G, et al., Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2204084119
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7329777
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S7 +/+: postnatal day 1 (more )
Note: Double labeled: green - Nefm; magenta - Myo7a (assay MGI:7329775).
Structure Level Pattern Image Note
TS27: organ of Corti Present S7_Minar2 +/+
Specimen S7 tm1b/tm1b: postnatal day 1; Minar2tm1b(KOMP)Wtsi/Minar2tm1b(KOMP)Wtsi (more )
Note: Double labeled: green - Nefm; magenta - Myo7a (assay MGI:7329775).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted S7_Minar2 tm1b/tm1b Reduction of nerve fibers around inner hair cells and dispersed distribution of nerve fibers toward outer hair cells.
Specimen 7A +/+ Base: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cochlea Present 7A +/+ Base
Specimen 7A tm1b/tm1b Base: postnatal day 1; Minar2tm1b(KOMP)Wtsi/Minar2tm1b(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS27: cochlea Present 7A tm1b/tm1b Base
Specimen 7A +/+ Middle: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cochlea Present 7A +/+ Middle
Specimen 7A tm1b/tm1b Middle: postnatal day 1; Minar2tm1b(KOMP)Wtsi/Minar2tm1b(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS27: cochlea Present 7A tm1b/tm1b Middle
Specimen 7A +/+ Apex: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cochlea Present 7A +/+ Apex
Specimen 7A tm1b/tm1b Apex: postnatal day 1; Minar2tm1b(KOMP)Wtsi/Minar2tm1b(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS27: cochlea Present 7A tm1b/tm1b Apex
Specimen 7B +/+ Base: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cochlea Present 7B +/+ Base
Specimen 7B tm1b/tm1b Base: postnatal day 14; Minar2tm1b(KOMP)Wtsi/Minar2tm1b(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 7B tm1b/tm1b Base Reduction in number of crossings of type II nerves.
Specimen 7B +/+ Middle: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cochlea Present 7B +/+ Middle
Specimen 7B tm1b/tm1b Middle: postnatal day 14; Minar2tm1b(KOMP)Wtsi/Minar2tm1b(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 7B tm1b/tm1b Middle Reduction in number of crossings of type II nerves.
Specimen 7B +/+ Apex: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cochlea Present 7B +/+ Apex
Specimen 7B tm1b/tm1b Apex: postnatal day 14; Minar2tm1b(KOMP)Wtsi/Minar2tm1b(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 7B tm1b/tm1b Apex Reduction in number of crossings of type II nerves.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory