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Gene Expression Data
Assay Details
Assay
Reference: J:321237 Edwards NA, et al., P66Shc, a key regulator of metabolism and mitochondrial ROS production, is dysregulated by mouse embryo culture. Mol Hum Reprod. 2016 Sep;22(9):634-47
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7328575
Gene symbol: Shc1
Gene name: src homology 2 domain-containing transforming protein C1
Antibody: anti-(phospho S36) p66Shc
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A: embryonic day 0.5 (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A Expression is throughout the cytoplasm.
Specimen 2B: embryonic day 1.0 (more )
Note: 2-cell stage embryo
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 2B Expression is throughout the cytoplasm.
Specimen 2C: embryonic day 2.0 (more )
Note: 4-cell stage embryo
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 2C Expression is throughout the cytoplasm.
Specimen 2D: embryonic day 2.5 (more )
Note: 8-cell non-compacted embryo
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present 2D Expression is throughout the cytoplasm.
Specimen 2E: embryonic day 3.0 (more )
Note: 8-16 cell compacted morula
Structure Level Pattern Image Note
TS3: compacted morula Present Regionally restricted 2E Expression is at the apical cell periphery.
Specimen 2F: embryonic day 3.5 (more )
Note: Blastocyst. Double labeled: green - Shc1; red - Cdx2 (assay MGI:7328577).
Structure Level Pattern Image Note
TS4: trophectoderm Present 2F Expression is at the cell periphery.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory